Figure 1

Schematic of our approach. (a) From a SNP array sample, , representing differences of aberrations with neighbors, and values, showing the overall aberrations, are generated using the wavelet transform. (b) The from multiple samples are summed in order to combine aberrations from multiple samples. (c) Focal aberrations are identified by clustering probes with their neighbors. (d) The values from multiple samples are summed to identify aberrations from multiple samples. (e) Broad aberration regions are identified if the summation of values across multiple samples are larger than a threshold of statistical significance the size of a chromosome arm.