CASP 7 target | Scoring function (a) | H-factor (%) | cRMS (Ã…) (b) | % ID (c) | DOPE (d) | QMEANnorm (e) |
|---|
| Â |
(1)
|
(2)
|
(3)
|
(4)
| Â | Â | Â | Â | Â |
T0295 | 1.0 | 1.9 | 1.3 | 3.8 | 19 | 1.67 | 46 | -33940 | 0.735 |
T0295* (f) | 1.0 | 1.9 | 1.9 | 3.8 | 21 | 1.71 | 46 | -24317 | 0.196 |
T0375 | 1.1 | 8.6 | 2.9 | 3.8 | 41 | 3.16 | 17 | -28442 | 0.546 |
T0287 | 7.0 | 8.1 | 7.5 | 7.5 | 75 | 5.81 | 16 | -18444 | 0.285 |
- (a) The four scoring functions included in the H-factor measure the quality of the secondary structure prediction (score (1)), the diversity of the sequence alignment (score (2)), the structural diversity of the models generated (score (3)), and the similarity of the predicted structures for the functional domains in the target, compared to the structures of the same domains found in the PDB (score (4)) (see text for detail)
- (b) Average cRMS (over Cα) between the 20 different models generated and the actual experimental structure for the target.
- (c) Sequence identity between the target sequence and the template sequence
- (d) DOPE scores from MODELLER [94]
- (e) QMEAN normalized score [95]
- (f) T0295* is the toy experiment in which the sequence alignment between the target T0295 and its framework has been deliberately modified (see text for details).
