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Table 3 Comparison of the H-factor with cRMS, DOPE and QMEAN scores to assess models generated for CASP7 targets from the free-modeling category

From: A quality metric for homology modeling: the H-factor

CASP 7 target

H-Factor (%)

cRMS (Ã…) (a)

DOPE (b)

QMEANnorm (c)

T0356_D1

48

4.9

-8908

0.242

T0356_D2

48

4.9

-13013

0.209

T0316_D3

49

6.0

-5488

0.176

T0356_D3

49

4.9

-9274

0.285

T0316_D2

51

5.8

-2980

0.110

T0307_D1

62

5.5

-12623

0.385

T0307

63

6.0

-13816

0.407

T0309

65

5.5

-4613

0.180

T0314

65

5.4

-9248

0.372

T0296

67

5.6

-35782

0.260

T0299

67

5.9

-17649

0.334

T0306

68

4.8

-7884

0.287

T0316_D1

68

5.6

-16102

0.214

T0299_D2

69

6.0

-7742

0.302

T0316

69

3.8

-31249

0.172

T0299_D1

70

6.2

-7641

0.250

  1. (a) cRMS (over Cα) between the average model and the actual experimental structure for the target.
  2. (b) DOPE scores from MODELLER [94]
  3. (c) QMEAN normalized score [95]