(A) Base triple interactions that were not previously recorded in the NCIR database. (B) Base triple interactions which were not listed in the NAIL library of query patterns but which were found to be present in the NCIR database. (C) Novel triple interactions that were neither recorded in the NCIR database nor listed in the NAIL query dataset. Hydrogen bonds from possibly protonated bases are marked with arrows and + at the protonated donor position. The geometric orientation labels have been abbreviated as: C=Cis glycosidic bond orientation, H=Hoogsteen Edge, T=Trans glycosidic bond orientation, S=Sugar edge, WC=Watson-Crick edge.