Figure 4

An example of successful retrieval but with poor structure alignments. The structure pair is from the morphing group of va2eznA-1l5bA in the Hinge Atlas dataset. (a) The open-form (green, ff9) and closed-form (blue, ff0) of Cyanovirin-N. (b) to (f) are structure alignments generated by jFATCAT, FASE, Fast, Matt-Rigid and Matt-Flexible respectively. The non-aligned regions are colored by gray. All methods ranked the closed-form of Cyanovirin-N at the top of 214 representative structures when the open-form of Cyanovirin-N as a query; nevertheless, FASE, Fast, Matt-Rigid and Matt-Flexible only aligned half portion of the query protein.