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Figure 1 | BMC Bioinformatics

Figure 1

From: Evolutionary sequence analysis of complete eukaryote genomes

Figure 1

Flowchart of multigenome intersection approach (MIA). 1) Complete genomes are reciprocally compared against themselves and all other genomes with BLAST. 2) Pairwise ortholog clusters are identified using similarity scores and imported into a local database. 3) The intersection between genomes is determined by iteratively comparing sequence identification tags and retaining those clusters showing panorthology. 4) Additional genomes are added and checked as in the previous step. 5) Sequence data files are generated for evolutionary analysis.

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