Figure 4

Examples of one-to-one exact mapping between Pfam families and SCOP domain families. The domains are graphed onto the PDB structures of their corresponding member proteins using Pymol. The first row shows Pfam domains and the second row shows their corresponding SCOP domains. The structure regions of Pfam domains are marked in green and those of SCOP domains are marked in blue. Red regions lie outside the SCOP or Pfam domains. The differences in the domain coverage on the structures indicate disagreement between the domain definitions. The differences are usually in domain boundaries. The PDB proteins 1e17A, 1o7fA, and 3htsB are used for the illustration.