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Figure 3 | BMC Bioinformatics

Figure 3

From: Meta-analysis discovery of tissue-specific DNA sequence motifs from mammalian gene expression data

Figure 3

Effect of block filtering of motifs resulting from the skeletal muscle CRMs versus randomly selected sequence sets. Shown here are the nonredundant motifs from five separate MultiFinder runs for both the muscle test set and the matched randoms. (A) Total number of motifs, belonging to either the skeletal muscle CRM set or the size-matched set of random sequences, that either passed or failed the blocks filtering step (y-axis), at different motif group specificity cutoffs (x-axis). (B) Percentage of motifs, at different group specificity scores cutoffs (x-axis), that passed the block filtering step (y-axis). (C) As in (A), except after merging motif results from 5 runs of the skeletal muscle CRM set and separately runs on 5 separate size-matched sets of random sequences. (D) As in (B), except after merging motif results from 5 runs of the skeletal muscle CRM set and separately runs on 5 separate size-matched sets of random sequences.

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