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Table 3 Validation of SNPs detected by QualitySNP and autoSNP in nineteen UniGene data sets of human.

From: QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyploid species

   

QualitySNP(D < = 0.6)

autoSNP

their overlap

chromosome

UniGene

Size

Time(m)

candidate SNPsa

confirmed

unconfirmed

Time(m)

candidate SNPsb

confirmed

unconfirmed

candidate SNPs

confirmed

unconfirmed

6

Hs.300701

3640

2

18

5 (27.8%)

13

150

6

0 (0%)

6

3

0(0%)

3

7

Hs.401316

1090

1

0

0 (0%)

0

3

4

0 (0%)

4

0

0(0%)

0

14

Hs.533717

1601

1

12

3 (25%)

9

26

166

1 (0.6%)

165

0

0(0%)

0

17

Hs.12956

622

1

10

2 (20%)

8

1

15

1 (6.7%)

14

9

1(11.11%)

8

19

Hs.515126

654

1

1

0 (0%)

1

2

44

0 (0%)

44

1

0(0%)

1

15

Hs.22543

847

1

10

1 (10%)

9

1

4

1 (25%)

3

1

1(100%)

0

2

Hs.468478

183

1

0

0 (0%)

0

1

0

0 (0%)

0

0

0(0%)

0

1

Hs.591503

200

1

6

2 (33.3%)

4

1

5

0 (0%)

5

3

0(0%)

3

6

Hs.567284

194

1

7

0 (0%)

7

1

8

0 (0%)

8

7

0(0%)

7

6

Hs.510172

282

1

1

0 (0%)

1

1

0

0 (0%)

0

0

0(0%)

0

17

Hs.406754

6453

2

49

25 (51%)

24

51

43

6 (14%))

37

14

5(35.71%)

9

14

Hs.510635

27193

4

535

198 (37%)

337

13

895

92 (10.3%)

803

143

86(60.14%)

57

7

Hs.61635

82

1

0

0 (0%)

0

1

0

0 (0%)

0

0

0(0%)

0

2

Hs.631881

355

1

5

0 (0%)

5

1

1

0 (0%)

1

0

0(0%)

0

8

Hs.104741

275

1

0

0 (0%)

0

1

0

0 (0%)

0

0

0(0%)

0

2

Hs.534639

1910

1

11

1 (9.1%)

10

6

9

0 (0%)

9

6

0(0%)

6

14

Hs.18069

1965

1

3

1 (33.3%)

2

1

1

0 (0%)

1

0

0(0%)

0

17

Hs.514220

6800

2

8

2 (25%)

6

267

13

0 (0%)

13

2

0(0%)

2

12

Hs.19192

397

1

1

0 (0%)

1

2

0

0 (0%)

0

0

0(0%)

0

Total

 

54743

 

677

240 (35.5%)

437

 

1214

101 (8.3%)

1113

189

93(49.21%)

96

  1. a Candidate SNPs predicted by QualitySNP; b candidate SNPs (score > = 50) predicted by autoSNP. confirmed: Candidate SNPs are considered as confirmed if they are present in dbSNP. Time (m): the minutes were used to run a program on each UniGene.