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Figure 7 | BMC Bioinformatics

Figure 7

From: From biophysics to evolutionary genetics: statistical aspects of gene regulation

Figure 7

Substitution rate in a population versus mutation rate in an individual. The ratio of these rates, uab/μab, depends on the product N ΔF ab of effective population size and fitness difference between the genotypes (in the relevant regime N 1, ΔF ab 1, N ΔF ab finite). The substitution rate uabis equal to μ ab for neutral mutations (ΔF ab = 0), reduced for deleterious mutations (ΔF ab < 0), and enhanced for advantageous mutations (ΔF ab > 0).

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