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Table 3 Deleted reactions for glycine production with E. Coli, using the iAF1260 metabolic model

From: An integrated network visualization framework towards metabolic engineering applications

Reaction Model ID Stoichiometric equation
Isiocitrate lyase R_ICL Isocitrate = > Succinate + Glyoxylate
Glycine cleavage R_GLYCL Glycine + NAD+ + Tetrahydrofolate = > NH4+ + 5,10-Methylenetetrahydrofolate + NADH + CO2
Phosphoenolpyruvate carboxylase R_PPC Oxaloacetate + Phosphate < = > Phosphoenolpyruvate + Bicarbonate
Phosphoribosyglycinamide formyltrasferase 2 R_GART 5-phospho-ribosyl-glycineamide + Formate + ATP <= > 5’-phosphoribosyl-N-formylglycineamide + ADP + Phosphate + H+