Table 3 Deleted reactions for glycine production with E. Coli, using the iAF1260 metabolic model
From: An integrated network visualization framework towards metabolic engineering applications
Reaction | Model ID | Stoichiometric equation |
|---|---|---|
Isiocitrate lyase | R_ICL | Isocitrate = > Succinate + Glyoxylate |
Glycine cleavage | R_GLYCL | Glycine + NAD+ + Tetrahydrofolate = > NH4+ + 5,10-Methylenetetrahydrofolate + NADH + CO2 |
Phosphoenolpyruvate carboxylase | R_PPC | Oxaloacetate + Phosphate < = > Phosphoenolpyruvate + Bicarbonate |
Phosphoribosyglycinamide formyltrasferase 2 | R_GART | 5-phospho-ribosyl-glycineamide + Formate + ATP <= > 5’-phosphoribosyl-N-formylglycineamide + ADP + Phosphate + H+ |