Integrating mean and variance heterogeneities to identify differentially expressed genes

BMC Bioinformatics

Table 2 The overlap of the discoveries of our IMVT and the genes which were testified to be involved in functional networks

AffyID	Gene	Adjusted MAS5*				MAS5**
AffyID	Gene	IMVT	STSD	MWT	WT	ST
201085_s_at	SON	0.0075	0.0021	0.0021	0.0023	2.15E-14
203868_s_at	VCAM1	0.0030	0.0004	0.0005	0.0005	2.03E-07
204524_at	PDPK1	0.0470	0.0328	0.0337	0.0346	7.12E-11
204600_at	EPHB3	0.0178	0.0165	0.0207	0.0213	2.83E-04
205008_s_at	CIB2	0.0387	0.0122	0.0117	0.0123	1.25E-06
205099_s_at	CCR1	0.0058	0.0104	0.0160	0.0165	6.55E-11
206788_s_at	CBFB	0.0003	4.34E-05	4.28E-05	4.71E-05	<1.00E-17
207961_x_at	MYH11	0.0001	0.0139	0.0370	0.0383	8.11E-06
208164_s_at	IL9R	0.0311	0.0074	0.0072	0.0077	4.05E-05
209876_at	GIT2	0.0024	0.0040	0.0053	0.0057	1.20E-08
211197_s_at	ICOSLG	0.0448	0.0423	0.0479	0.0487	3.28E-05
211699_x_at	HBA1	0.0455	0.3238	0.3632	0.3667	2.70E-03
212514_x_at	DDX3X	0.0002	3.06E-05	2.73E-05	3.10E-05	2.22E-16
213446_s_at	IQGAP1	0.0082	0.0306	0.0400	0.0413	8.37E-10
217557_s_at	CPM	0.0347	0.2422	0.2678	0.2701	1.61E-03
219599_at	EIF4B	0.0006	0.0005	0.0018	0.0019	5.80E-14

*These raw p values of the heterogeneity tests based on the calibrated expression levels after adjusting for age, menopausal status, and the background structure
*These raw p values of Student t tests in Pan et al. [16] based on the MAS5 normalized data before adjusting for any of age, menopausal status, and the background structure

ISSN: 1471-2105