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Fig. 2 | BMC Bioinformatics

Fig. 2

From: JACUSA: site-specific identification of RNA editing events from replicate sequencing data

Fig. 2

Summary of data generation for in silico benchmark. Description of the data generation for in silico RDD and RRD detection. In total 1 DNA sample and 2x15 RNA samples (I+II) are simulated. DNA and RNA reads are simulated from chromosome 1 of human genome. Candidate SNPs and variant sites are created in regions that are covered by all simulated BAM files. Depending on the comparison, SNPs and variant sites are inserted into BAM files. SNPs are only implanted in the cDNA vs. cDNA setup and function there as noise

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