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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Using structural knowledge in the protein data bank to inform the search for potential host-microbe protein interactions in sequence space: application to Mycobacterium tuberculosis

Fig. 1

General idea behind sequence-based PPI prediction. These approaches make use of homology relationships and knowledge about protein interaction networks. An interaction is proposed to occur between the query protein Q and the protein T2, if Q shares similarity with the protein T1 on the sequence level and T1 is experimentally known to interact with T2

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