Table 3 All 11 viral integration sites identified in whole genome sequencing data from two HPV-positive cell lines (SiHa and HeLa) and two cervical carcinomas (T4931 and T6050) using HGT-ID
Sample ID (coverage) | Affected Gene | Function of integration site | Integrated Position | Score | Reported and validateda | Identified by VirusFinder 2.0 |
|---|---|---|---|---|---|---|
HELA (40x) | CCAT1 | intron | chr8 128,230,630 | 1273.7 | yes | yes |
CCAT1 | upstream | chr8 128,233,368 | 121.2 | yes | no | |
CCAT1 | upstream | chr8 128,234,256 | 180.3 | yes | no | |
CCAT1 | upstream | chr8 128,241,549 | 235.7 | yes | yes | |
SIHA (37×) | KLF12 | downstream | chr13 74,087,563 | 158.0 | yes | yes |
KLF12 | downstream | chr13 73,788,864 | 136.4 | yes | yes | |
T4931 (41×) | GLI2 | intron | chr2 121,670,164 | 2.4 | yes | yes |
GLI2 | intron | chr2 121,687,141 | 213.4 | yes | no | |
GLI2 | intron | chr2 121,688,179 | 48.9 | yes | no | |
T6050 (42×) | KLF12 | downstream | chr13 74,230,820 | 305.1 | yes | no |
KLF12 | downstream | chr13 74,231,436 | 342.2 | yes | yes |