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Table 3 Predicted conserved and exclusive LEs for two clustered groups: vertebrate and invertebrate iridovirus subfamiliese. (*N/A represents the predicted segments possessing missing residues among the five virtual structures)

From: A voting mechanism-based linear epitope prediction system for the host-specific Iridoviridae family

Iridoviridae groups

Predictive LEs of representative peptide

Residue Location

RMSDs of structural alignment(Ã…)

Iridoviridae family (Conserved LEs)

KAVGYDNMIGN

(IIV)

Iridovirus:145~155

1.233

KRNGYDNMIGN

Chloriridovirus:46~56

KRIGYDNMIGN

(VIV)

Lymphocystivirus:146~156

0.063

KRIGYDNMIGN

Megalocystivirus:146~156

KQSGYNKMIGM

Ranavirus:141~151

SNYTTASPVITSTT

(IIV)

Iridovirus:323~336

2.685

SNYGTSSPVVSGTS

Chloriridovirus:222~233

SNYTSSSPVIFDGG

(VIV)

Lymphocystivirus:315~327

0.268

SNYTCVTPVNGPGN

Megalocystivirus:320~332

SNYTAASPVYVNNK

Ranavirus:311~323

RLNHMGSD

(IIV)

Iridovirus:360~367

1.792

RLGTMGSD

Chloriridovirus:258~265

RLNEMGSE

(VIV)

Lymphocystivirus:354~359

0.231

RLANMGVE

Megalocystivirus:356~363

RLHQMGVD

Ranavirus:346~353

GAAGTGPAGSGQNFPQT

(IIV)

Iridovirus:424~442

2.385

ASTGAGDGAGANYNQS

Chloriridovirus:324~339

TAGGNGGNTSG

(VIV)

Lymphocystivirus:418~428

0.308

AAAGGGNNNSG

Megalocystivirus: 422~432

TAAGGGGNGTG

Ranavirus:412~422

VIV

(Exclusive LEs)

TIDMTQPVDS

TSDMTNPTPA

RSDLVGGITN

Lymphocystivirus:157~166

N/A*

Megalocystivirus: 157~166

Ranavirus:152~161

IIV

(Exclusive LEs)

VALPTAALPYNE

VSLPTAALPYNE

Iridovirus:193~203

2.683

Chloriridovirus:92~102

VASQTVVPVVG

TTGNPYQTIDV

Iridovirus:226~236

N/A*

Chloriridovirus:125~135