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Table 3 Predicted conserved and exclusive LEs for two clustered groups: vertebrate and invertebrate iridovirus subfamiliese. (*N/A represents the predicted segments possessing missing residues among the five virtual structures)

From: A voting mechanism-based linear epitope prediction system for the host-specific Iridoviridae family

Iridoviridae groups Predictive LEs of representative peptide Residue Location RMSDs of structural alignment(Å)
Iridoviridae family (Conserved LEs) KAVGYDNMIGN (IIV) Iridovirus:145~155 1.233
KRNGYDNMIGN Chloriridovirus:46~56
KRIGYDNMIGN (VIV) Lymphocystivirus:146~156 0.063
KRIGYDNMIGN Megalocystivirus:146~156
KQSGYNKMIGM Ranavirus:141~151
SNYTTASPVITSTT (IIV) Iridovirus:323~336 2.685
SNYGTSSPVVSGTS Chloriridovirus:222~233
SNYTSSSPVIFDGG (VIV) Lymphocystivirus:315~327 0.268
SNYTCVTPVNGPGN Megalocystivirus:320~332
SNYTAASPVYVNNK Ranavirus:311~323
RLNHMGSD (IIV) Iridovirus:360~367 1.792
RLGTMGSD Chloriridovirus:258~265
RLNEMGSE (VIV) Lymphocystivirus:354~359 0.231
RLANMGVE Megalocystivirus:356~363
RLHQMGVD Ranavirus:346~353
GAAGTGPAGSGQNFPQT (IIV) Iridovirus:424~442 2.385
ASTGAGDGAGANYNQS Chloriridovirus:324~339
TAGGNGGNTSG (VIV) Lymphocystivirus:418~428 0.308
AAAGGGNNNSG Megalocystivirus: 422~432
TAAGGGGNGTG Ranavirus:412~422
VIV
(Exclusive LEs)
TIDMTQPVDS
TSDMTNPTPA
RSDLVGGITN
Lymphocystivirus:157~166 N/A*
Megalocystivirus: 157~166
Ranavirus:152~161
IIV
(Exclusive LEs)
VALPTAALPYNE
VSLPTAALPYNE
Iridovirus:193~203 2.683
Chloriridovirus:92~102
VASQTVVPVVG
TTGNPYQTIDV
Iridovirus:226~236 N/A*
Chloriridovirus:125~135