Fig. 1
From: Cell cycle control and environmental response by second messengers in Caulobacter crescentus
The asymmetric cell cycle of C. crescentus. A stalked cell is non-motile with a holdfast. A swarmer cell is motile with pili and a flagellum. A swarmer cell transforms into a stalked cell before DNA replication commences. CtrA regulates cell cycle progression in time and space. CtrA is eliminated during the G1-to-S transition. The green intensity indicates increasing concentrations of CtrA during cell cycle progression. ClpXP, a protease specific for CtrA, shows up at the old pole of a cell to degrade CtrA. c-di-GMP cooperates with ClpXP for CtrA proteolysis