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Table 5 Simulations under different conditions

From: Cell cycle control and environmental response by second messengers in Caulobacter crescentus

 

[Gln]

10000 μM

2000 μM

1000 μM

100 μM

10 μM

1 μM

 

cdG range

0.01-0.28*

0.01-0.26

0.01-0.25

0-0.09

0-0.03

0-0.02**

 

(p)ppGpp (μM)

118

150

187

582

895

939

 

GTP (μM)

1221

1192

1156

787

493

452

[PEP]=300 μM

\(\frac {\text {[(p)ppGpp]}}{\text {[GTP]}}\)

0.10

0.13

0.16

0.74

1.8

2.1

[Pyr]=1500 μM

GMP (μM)

81

79

77

52

33

30

 

EI ∼ P (μM)

0.5

0.6

0.8

2.0

3.2

3.4

 

NPr ∼ P (μM)

1.6

1.9

2.4

6.1

9.5

10.2

 

EIIA ∼ P (μM)

1.6

1.9

2.4

6.1

9.5

10.2

 

cdG range

0.01-0.20

0.01-0.17***

0.01-0.13***

0-0.02

0-0.01

0-0.01

 

(p)ppGpp (μM)

294

371

458

993

1160

1178

 

GTP (μM)

1056

984

902

401

244

227

[PEP]=2800 μM

\(\frac {\text {[(p)ppGpp]}}{\text {[GTP]}}\)

0.28

0.38

0.51

2.5

4.8

5.2

[Pyr]=900 μM

GMP (μM)

70

66

60

27

16

15

 

EI ∼ P (μM)

1.1

1.4

1.6

3.7

5.2

5.4

 

NPr ∼ P (μM)

3.4

4.2

4.9

11.1

15.6

16.3

 

EIIA ∼ P (μM)

3.4

4.2

4.9

11.1

15.6

16.3

  1. *Proposed to be under condition of ammonia with high carbon
  2. **Proposed to be under condition of nitrogen starvation
  3. ***Proposed to be under condition of ammonia with limited carbon