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Table 10 The intersection of the first 10 pathways (sorted by the relevance of p value \(\le 0.005\)) obtained from pathDIP performing PEA using TC genes lists and the KEGG database

From: Using BioPAX-Parser (BiP) to enrich lists of genes or proteins with pathway data

Pathway Name

p value

FDRc

Bc

(1) MicroRNAs in cancer

1.95 × 10\(^{-29}\)

6.18 × 10\(^{-27}\)

6.18 × 10\(^{-27}\)

(2)Endocytosis

2.82 × 10\(^{-27}\)

4.47 × 10\(^{-25}\)

8.94 × 10\(^{-25}\)

(3)Pathways in cancer

2.71 × 10\(^{-25}\)

2.86 × 10\(^{-23}\)

8.59 × 10\(^{-23}\)

(4)PI3K-Akt signaling

4.67 × 10\(^{-24}\)

3.70 × 10\(^{-22}\)

1.48 × 10\(^{-21}\)

(5)Proteoglycans in cancer

1.04 × 10\(^{-21}\)

6.58 × 10\(^{-20}\)

3.29 × 10\(^{-19}\)

(6)Human papillomavirus infection

5.76 × 10\(^{-19}\)

2.61 × 10\(^{-17}\)

1.83 × 10\(^{-16}\)

(7)Focal adhesion

5.79 × 10\(^{-17}\)

2.29 × 10\(^{-15}\)

1.84 × 10\(^{-14}\)

(8)MAPK signaling

7.28 × 10\(^{-16}\)

2.31 × 10\(^{-14}\)

2.31 × 10\(^{-13}\)

(9)Phagosome

2.29 × 10\(^{-15}\)

6.59 × 10\(^{-14}\)

7.25 × 10\(^{-13}\)

(10)Regulation of actin cytoskeleton

8.49 × 10\(^{-15}\)

1.92 × 10\(^{-13}\)

2.69 × 10\(^{-12}\)

  1. In the table, FDRc represents the corrected p value using FDR corrector, and Bc refers to the corrected p value using Bonferroni corrector