Table 13 The intersection of the first 10 pathways (sorted by the relevance of p value \(\le 0.005\)) obtained from BiP performing PEA using EC genes lists and the Reactome database
From: Using BioPAX-Parser (BiP) to enrich lists of genes or proteins with pathway data
Pathway Name | p value | FDRc | Bc |
|---|---|---|---|
(1) Metabolism of proteins | 2.35 × 10\(^{-182}\) | 4.83 × 10\(^{-179}\) | 4.83 × 10\(^{-179}\) |
(2) Metabolism | 3.89 × 10\(^{-173}\) | 4.00 × 10\(^{-170}\) | 8.00 × 10\(^{-170}\) |
(3) Cellular responses to external stimuli | 5.22 × 10\(^{-160}\) | 3.57 × 10\(^{-157}\) | 1.07 × 10\(^{-156}\) |
(4) Signaling by Receptor Tyrosine Kinases | 2.82 × 10\(^{-159}\) | 1.45 × 10\(^{-156}\) | 5.80 × 10\(^{-156}\) |
(5) Cellular responses to stress | 5.82 × 10\(^{-157}\) | 2.39 × 10\(^{-154}\) | 1.20 × 10\(^{-153}\) |
(6) Cell Cycle | 1.30 × 10\(^{-151}\) | 4.46 × 10\(^{-149}\) | 2.67 × 10\(^{-148}\) |
(7) Post-translational protein modification | 3.30 × 10\(^{-150}\) | 9.68 × 10\(^{-148}\) | 6.77 × 10\(^{-147}\) |
(8) Cell Cycle, Mitotic | 7.04 × 10\(^{-150}\) | 1.81 × 10\(^{-147}\) | 1.44 × 10\(^{-146}\) |
(9) Mitotic G1-G1/S phases | 7.04 × 10\(^{-150}\) | 1.61 × 10\(^{-147}\) | 1.44 × 10\(^{-146}\) |
(10) Cellular Senescence | 3.54 × 10\(^{-149}\) | 7.27 × 10\(^{-147}\) | 7.27 × 10\(^{-146}\) |