Table 5 The first 10 enriched pathways using the whole list of relevant DEGs obtained from the AML GSE24739 data set without using DEG group classification
PathwayName | Pvalue | FDRC | BonfC | \(|lg_{2}(P_{value})|\) | \(|lg_{2}(FDR(P_{value})|\) | \(|lg_{2}Bonf(P_{value})|\) |
|---|---|---|---|---|---|---|
(1) Signaling pathways | 5.29E−13 | 4.87E−10 | 4.87E−10 | 30.94 | 30.94 | 30.94 |
(2) Hemostasis | 5.36E−13 | 2.47E−10 | 4.93E−10 | 31.92 | 30.92 | 30.92 |
(3) Developmental biology | 9.86E−10 | 3.02E−07 | 9.07E−07 | 21.66 | 20.07 | 20.07 |
(4) Signaling by interleukins | 1.37E−09 | 3.15E−07 | 1.26E−06 | 21.60 | 19.60 | 19.60 |
(5) Cell surface interactions at the vascular wall | 1.94E−09 | 3.56E−07 | 1.78E−06 | 21.42 | 19.10 | 19.10 |
(6) Cytokine signaling in immune system | 5.40E−09 | 8.28E−07 | 4.97E−06 | 20.20 | 17.62 | 17.62 |
(7) Muscle contraction | 9.65E−09 | 1.27E−06 | 8.88E−06 | 19.59 | 16.78 | 16.78 |
(8) Signaling by GPCR | 1.83E−08 | 2.10E−06 | 1.68E−05 | 18.86 | 15.86 | 15.86 |
(9) GPCR downstream signalling | 2.09E−08 | 2.14E−06 | 1.93E−05 | 18.83 | 15.66 | 15.66 |
(10) Cardiac conduction | 2.12E−08 | 1.95E−06 | 1.95E−05 | 18.97 | 15.65 | 15.65 |