Fig. 14
From: Genomic and immunogenomic analysis of three prognostic signature genes in LUAD
Regulatory networks of target genes and immune checkpoint-related genes. A Cross-talk between HOXC8 and CD274; B Cross-talk between HOXC8 and HAVCR2; C Cross-talk between NFE2 and CTLA4; D Cross-talk between NFE2 and PDCD1; E Cross-talk between NFE2 and PDCD1LG2; F Cross-talk between MMP12 and CD274; G Cross-talk between MMP12 and PDCD1; H Cross-talk between MMP12 and CTLA4; I Cross-talk between MMP12 and HAVCR2; J Cross-talk between MMP12 and PDCD1LG2; K Cross-talk between MMP12 and TIGIT. Circles represent genes, triangles represent enzymes, squares represent transcription factors, lines represent interactions, and the numbers on the lines represent the number of studies of interactions between genes that were experimentally validated or data-mined