Volume 10 Supplement 2

Selected Proceedings of the First Summit on Translational Bioinformatics 2008


Edited by Atul J Butte, Indra Neil Sarkar, Marco Ramoni, Yves Lussier and Olga Troyanskaya

The First Summit on Translational Bioinformatics 2008. Go to conference site.

San Francisco, CA, USA

10-12 March 2008

  1. Proceedings

    Ontology-driven indexing of public datasets for translational bioinformatics

    The volume of publicly available genomic scale data is increasing. Genomic datasets in public repositories are annotated with free-text fields describing the pathological state of the studied sample. These ann...

    Nigam H Shah, Clement Jonquet, Annie P Chiang, Atul J Butte, Rong Chen and Mark A Musen

    BMC Bioinformatics 2009 10(Suppl 2):S1

    Published on: 5 February 2009

  2. Proceedings

    Ontology driven integration platform for clinical and translational research

    Semantic Web technologies offer a promising framework for integration of disparate biomedical data. In this paper we present the semantic information integration platform under development at the Center for Cl...

    Parsa Mirhaji, Min Zhu, Mattew Vagnoni, Elmer V Bernstam, Jiajie Zhang and Jack W Smith

    BMC Bioinformatics 2009 10(Suppl 2):S2

    Published on: 5 February 2009

  3. Proceedings

    Metadata mapping and reuse in caBIG™

    This paper proposes that interoperability across biomedical databases can be improved by utilizing a repository of Common Data Elements (CDEs), UML model class-attributes and simple lexical algorithms to facil...

    Isaac Kunz, Ming-Chin Lin and Lewis Frey

    BMC Bioinformatics 2009 10(Suppl 2):S4

    Published on: 5 February 2009

  4. Proceedings

    Phenotype forecasting with SNPs data through gene-based Bayesian networks

    Bayesian networks are powerful instruments to learn genetic models from association studies data. They are able to derive the existing correlation between genetic markers and phenotypic traits and, at the same...

    Alberto Malovini, Angelo Nuzzo, Fulvia Ferrazzi, Annibale A Puca and Riccardo Bellazzi

    BMC Bioinformatics 2009 10(Suppl 2):S7

    Published on: 5 February 2009

  5. Proceedings

    BioProspecting: novel marker discovery obtained by mining the bibleome

    BioProspecting is a novel approach that enabled our team to mine data related to genetic markers from the New England Journal of Medicine (NEJM) utilizing SNOMED CT and the Human Gene Onotology (HUGO). The Bio...

    Peter L Elkin, Mark S Tuttle, Brett E Trusko and Steven H Brown

    BMC Bioinformatics 2009 10(Suppl 2):S9

    Published on: 5 February 2009

  6. Proceedings

    Towards bioinformatics assisted infectious disease control

    This paper proposes a novel framework for bioinformatics assisted biosurveillance and early warning to address the inefficiencies in traditional surveillance as well as the need for more timely and comprehensi...

    Vitali Sintchenko, Blanca Gallego, Grace Chung and Enrico Coiera

    BMC Bioinformatics 2009 10(Suppl 2):S10

    Published on: 5 February 2009

  7. Proceedings

    Leveraging existing biological knowledge in the identification of candidate genes for facial dysmorphology

    In response to the frequently overwhelming output of high-throughput microarray experiments, we propose a methodology to facilitate interpretation of biological data in the context of existing knowledge. Throu...

    Hannah J Tipney, Sonia M Leach, Weiguo Feng, Richard Spritz, Trevor Williams and Lawrence Hunter

    BMC Bioinformatics 2009 10(Suppl 2):S12

    Published on: 5 February 2009

  8. Proceedings

    Identifying hypothetical genetic influences on complex disease phenotypes

    Statistical interactions between disease-associated loci of complex genetic diseases suggest that genes from these regions are involved in a common mechanism impacting, or impacted by, the disease. The computa...

    Benjamin J Keller and Richard C McEachin

    BMC Bioinformatics 2009 10(Suppl 2):S13

    Published on: 5 February 2009