Citation Impact
3.242 - 2-year Impact Factor
3.213 - 5-year Impact Factor
1.156 - Source Normalized Impact per Paper (SNIP)
1.626 - SCImago Journal Rank (SJR)
Usage
4,058,323 downloads
Social Media Impact
6067 mentions
Volume 11 Supplement 1
Edited by Laxmi Parida and Gene Myers
The Eighth Asia Pacific Bioinformatics Conference (APBC 2010). Go to conference site.
Bangalore, India18-21 January 2010
Page 1 of 2
Citation: BMC Bioinformatics 2010 11(Suppl 1):I1
As a novel cancer diagnostic paradigm, mass spectroscopic serum proteomic pattern diagnostics was reported superior to the conventional serologic cancer biomarkers. However, its clinical use is not fully valid...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S1
MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in important cell functions, there is a growing inte...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S2
Many biological functions involve various protein-protein interactions (PPIs). Elucidating such interactions is crucial for understanding general principles of cellular systems. Previous studies have shown the...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S3
Tandem mass spectrometry (MS/MS) has become the primary way for protein identification in proteomics. A good score function for measuring the match quality between a peptide and an MS/MS spectrum is instrument...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S4
Feature selection techniques are critical to the analysis of high dimensional datasets. This is especially true in gene selection from microarray data which are commonly with extremely high feature-to-sample r...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S5
In supervised learning, traditional approaches to building a classifier use two sets of examples with pre-defined classes along with a learning algorithm. The main limitation of this approach is that examples fro...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S6
Defensins comprise a group of antimicrobial peptides, widely recognized as important elements of the innate immune system in both animals and plants. Cationicity, rather than the secondary structure, is believ...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S7
The large amount of high-throughput genomic data has facilitated the discovery of the regulatory relationships between transcription factors and their target genes. While early methods for discovery of transcr...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S8
Prediction of protein structural classes (α, β, α + β and α/β) from amino acid sequences is of great importance, as it is beneficial to study protein function, regulation and interactions. Many methods have been ...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S9
Post-translational modifications (PTMs) have a key role in regulating cell functions. Consequently, identification of PTM sites has a significant impact on understanding protein function and revealing cellular...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S10
Improving the accuracy and efficiency of motif recognition is an important computational challenge that has application to detecting transcription factor binding sites in genomic data. Closely related to motif...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S11
Metagenomics is the study of environmental samples using sequencing. Rapid advances in sequencing technology are fueling a vast increase in the number and scope of metagenomics projects. Most metagenome sequen...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S12
This article has been withdrawn from the public domain because of significant plagiarism. In the light of this situation, BioMed Central regrets that this article is no longer available. The authors apologise ...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S13
Small non-coding RNAs (21 to 24 nucleotides) regulate a number of developmental processes in plants and animals by silencing genes using multiple mechanisms. Among these, the most conserved classes are microRN...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S14
MapReduce is a parallel framework that has been used effectively to design large-scale parallel applications for large computing clusters. In this paper, we evaluate the viability of the MapReduce framework fo...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S15
The classification of protein sequences using string algorithms provides valuable insights for protein function prediction. Several methods, based on a variety of different patterns, have been previously propo...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S16
Prediction of protein localization in subnuclear organelles is more challenging than general protein subcelluar localization. There are only three computational models for protein subnuclear localization thus ...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S17
Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs may influence the disease risk individually...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S18
Antibacterial peptides are one of the effecter molecules of innate immune system. Over the last few decades several antibacterial peptides have successfully approved as drug by FDA, which has prompted an inter...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S19
Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their similarity to known disease genes. Most of exis...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S20
Recombinant protein production is a useful biotechnology to produce a large quantity of highly soluble proteins. Currently, the most widely used production system is to fuse a target protein into different vec...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S21
MicroRNA (miRNA) expression profiling data has recently been found to be particularly important in cancer research and can be used as a diagnostic and prognostic tool. Current approaches of tumor classificatio...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S22
Keyword matching or ID matching is the most common searching method in a large database of protein-protein interactions. They are purely syntactic methods, and retrieve the records in the database that contain...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S23
Folding of a protein into its three dimensional structure is influenced by both local and global interactions within a protein. Higher order residue interactions, like pairwise, triplet and quadruplet ones, pl...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S24
Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful information to understand how biological syst...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S25
Human Immunodeficiency Virus type 1 (HIV-1), the causative agent of Acquired Immune Deficiency Syndrome (AIDS), exhibits very high genetic diversity with different variants or subtypes prevalent in different p...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S26
Finding sequences of evolutionary operations that transform one genome into another is a classical problem in comparative genomics. While most of the genome rearrangement algorithms assume that there is exactl...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S27
Traditional algorithms for hidden Markov model decoding seek to maximize either the probability of a state path or the number of positions of a sequence assigned to the correct state. These algorithms provide ...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S28
It has been apparent in the last few years that small non coding RNAs (ncRNA) play a very significant role in biological regulation. Among these microRNAs (miRNAs), 22-23 nucleotide small regulatory RNAs, have...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S29
The study of genome rearrangements has become a mainstay of phylogenetics and comparative genomics. Fundamental in such a study is the median problem: given three genomes find a fourth that minimizes the sum o...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S30
Understanding of secondary metabolic pathway in plant is essential for finding druggable candidate enzymes. However, there are many enzymes whose functions are not yet discovered in organism-specific metabolic...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S31
Pathways in biological system often cooperate with each other to function. Changes of interactions among pathways tightly associate with alterations in the properties and functions of the cell and hence altera...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S32
Glycobiology pertains to the study of carbohydrate sugar chains, or glycans, in a particular cell or organism. Many computational approaches have been proposed for analyzing these complex glycan structures, wh...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S33
Proteins show a great variety of 3D conformations, which can be used to infer their evolutionary relationship and to classify them into more general groups; therefore protein structure alignment algorithms are...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S34
Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interaction data as well as functional annotation ...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S35
RNA structure prediction problem is a computationally complex task, especially with pseudo-knots. The problem is well-studied in existing literature and predominantly uses highly coupled Dynamic Programming (D...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S36
Introduction of spaced speeds opened a way of sensitivity improvement in homology search without loss of search speed. Since then, the efforts of finding optimal seed which maximizes the sensitivity have been ...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S37
Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among species. While previous works in the field perf...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S38
The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy function have been proposed to ease the comput...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S39
Existing hidden Markov model decoding algorithms do not focus on approximately identifying the sequence feature boundaries.
Citation: BMC Bioinformatics 2010 11(Suppl 1):S40
One important goal of structural bioinformatics is to recognize and predict the interactions between protein binding sites and RNA. Recently, a comprehensive analysis of ribosomal proteins and their interactio...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S41
Genomic data provide a wealth of new information for phylogenetic analysis. Yet making use of this data requires phylogenetic methods that can efficiently analyze extremely large data sets and account for proc...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S42
In the yeast Saccharomyces cerevisiae, interactions between galactose, Gal3p, Gal80p, and Gal4p determine the transcriptional status of the genes required for the galactose utilization. Increase in the cellular g...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S43
The current advances in electron cryo-microscopy technique have made it possible to obtain protein density maps at about 6-10 Å resolution. Although it is hard to derive the protein chain directly from such a ...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S44
Haplotype-based approaches have been extensively studied for case-control association mapping in recent years. It has been shown that haplotype methods can provide more consistent results comparing to single-l...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S45
Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searching a large database of protein structures i...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S46
Type III secretion system (T3SS) is a specialized protein delivery system in gram-negative bacteria that injects proteins (called effectors) directly into the eukaryotic host cytosol and facilitates bacterial ...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S47
Flavin binding proteins (FBP) plays a critical role in several biological functions such as electron transport system (ETS). These flavoproteins contain very tightly bound, sometimes covalently, flavin adenine...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S48
Thermophilic proteins sustain themselves and function at higher temperatures. Despite their structural and functional similarities with their mesophilic homologues, they show enhanced stability. Various compar...
Citation: BMC Bioinformatics 2010 11(Suppl 1):S49
Citation Impact
3.242 - 2-year Impact Factor
3.213 - 5-year Impact Factor
1.156 - Source Normalized Impact per Paper (SNIP)
1.626 - SCImago Journal Rank (SJR)
Usage
4,058,323 downloads
Social Media Impact
6067 mentions