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Volume 11 Supplement 6

Proceedings of the Seventh Annual MCBIOS Conference. Bioinformatics: Systems, Biology, Informatics and Computation

Proceedings

Edited by Jonathan D Wren (Senior Editor), Dan Berleant, Susan M Bridges, Doris M Kupfer and Edward J Perkins

Seventh Annual MCBIOS Conference. Bioinformatics: Systems, Biology, Informatics and Computation. Go to conference site.

Jonesboro, AR, USA19-20 February 2010

  1. Lipoxygenases (LOX) play pivotal roles in the biosynthesis of leukotrienes and other biologically active potent signalling compounds. Developing inhibitors for LOX is of high interest to researchers. Modelling...

    Authors: Shuju Bai, Tianchuan Du and Ebrahim Khosravi
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S2
  2. Advances in microbial genomics and bioinformatics are offering greater insights into the emergence and spread of foodborne pathogens in outbreak scenarios. The Food and Drug Administration (FDA) has developed ...

    Authors: Hong Fang, Joshua Xu, Don Ding, Scott A Jackson, Isha R Patel, Jonathan G Frye, Wen Zou, Rajesh Nayak, Steven Foley, James Chen, Zhenqiang Su, Yanbin Ye, Steve Turner, Steve Harris, Guangxu Zhou, Carl Cerniglia…
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S4
  3. Endocrine disruptors (EDs) and their broad range of potential adverse effects in humans and other animals have been a concern for nearly two decades. Many putative EDs are widely used in commercial products re...

    Authors: Don Ding, Lei Xu, Hong Fang, Huixiao Hong, Roger Perkins, Steve Harris, Edward D Bearden, Leming Shi and Weida Tong
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S5
  4. Recent advances in high-throughput genotyping technology are paving the way for research in personalized medicine and nutrition. However, most of the genetic markers identified from association studies account...

    Authors: Joshua Xu, Carolyn Wise, Vijayalakshmi Varma, Hong Fang, Baitang Ning, Huixiao Hong, Weida Tong and Jim Kaput
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S6
  5. Finding reliable gene markers for accurate disease classification is very challenging due to a number of reasons, including the small sample size of typical clinical data, high noise in gene expression measure...

    Authors: Junjie Su, Byung-Jun Yoon and Edward R Dougherty
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S8
  6. Bovine Viral Diarrhea Virus (BVDV) infection is widespread in cattle worldwide, causing important economic losses. Pathogenesis of the disease caused by BVDV is complex, as each BVDV strain has two biotypes: n...

    Authors: Mais Ammari, Fiona M McCarthy, Bindu Nanduri and Lesya M Pinchuk
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S9
  7. The Affymetrix GeneChip® system is a commonly used platform for microarray analysis but the technology is inherently expensive. Unfortunately, changes in experimental planning and execution, such as the unavailab...

    Authors: Zhining Wen, Charles Wang, Quan Shi, Ying Huang, Zhenqiang Su, Huixiao Hong, Weida Tong and Leming Shi
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S10
  8. Until quite recently spinal disorder problems in the U.S. have been operated by fusing cervical vertebrae instead of replacement of the cervical disc with an artificial disc. Cervical disc replacement is a rec...

    Authors: Tansel Halic, Sinan Kockara, Coskun Bayrak and Richard Rowe
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S11
  9. Enzyme dynamics has recently been shown to be crucial for structure-function relationship. Among various structure dynamics analysis platforms, HDX (hydrogen deuterium exchange) mass spectrometry stands out as...

    Authors: Ugur Uzuner, Weibing Shi, Lantao Liu, Sanmin Liu, Susie Y Dai and Joshua S Yuan
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S12
  10. Searching the enormous amount of information available in biomedical literature to extract novel functional relationships among genes remains a challenge in the field of bioinformatics. While numerous (softwar...

    Authors: Elina Tjioe, Michael W Berry and Ramin Homayouni
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S14
  11. Traditional genome annotation systems were developed in a very different computing era, one where the World Wide Web was just emerging. Consequently, these systems are built as centralized black boxes focused ...

    Authors: Daniel J Quest, Miriam L Land, Thomas S Brettin and Robert W Cottingham
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S15
  12. Protein-protein interactions (PPIs) play a crucial role in initiating infection in a host-pathogen system. Identification of these PPIs is important for understanding the underlying biological mechanism of inf...

    Authors: Ranjit Kumar and Bindu Nanduri
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S16
  13. A number of models and algorithms have been proposed in the past for gene regulatory network (GRN) inference; however, none of them address the effects of the size of time-series microarray expression data in ...

    Authors: Vijender Chaitankar, Preetam Ghosh, Edward J Perkins, Ping Gong and Chaoyang Zhang
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S19
  14. Determining the secondary structure of RNA from the primary structure is a challenging computational problem. A number of algorithms have been developed to predict the secondary structure from the primary stru...

    Authors: Denise R Koessler, Debra J Knisley, Jeff Knisley and Teresa Haynes
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S21
  15. PHB (Prohibitin) gene family is involved in a variety of functions important for different biological processes. PHB genes are ubiquitously present in divergent species from prokaryotes to eukaryotes. Human PH...

    Authors: Chao Di, Wenying Xu, Zhen Su and Joshua S Yuan
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S22
  16. The aggregates of a protein called, ‘Aβ’ found in brains of Alzheimer’s patients are strongly believed to be the cause for neuronal death and cognitive decline. Among the different forms of Aβ aggregates, smal...

    Authors: Preetam Ghosh, Amit Kumar, Bhaswati Datta and Vijayaraghavan Rangachari
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S24
  17. Aspergillus flavus Link:Fr, an opportunistic fungus that produces aflatoxin, is pathogenic to maize and other oilseed crops. Aflatoxin is a potent carcinogen, and its presence markedly reduces the value of grain....

    Authors: Rowena Y Kelley, Cathy Gresham, Jonathan Harper, Susan M Bridges, Marilyn L Warburton, Leigh K Hawkins, Olga Pechanova, Bela Peethambaran, Tibor Pechan, Dawn S Luthe, J E Mylroie, Arunkanth Ankala, Seval Ozkan, W B Henry and W P Williams
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S25
  18. Computer-aided segmentation and border detection in dermoscopic images is one of the core components of diagnostic procedures and therapeutic interventions for skin cancer. Automated assessment tools for dermo...

    Authors: Sinan Kockara, Mutlu Mete, Bernard Chen and Kemal Aydin
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S26
  19. An introgression library is a family of near-isogenic lines in a common genetic background, each of which carries one or more genomic regions contributed by a donor genome. Near-isogenic lines are powerful gen...

    Authors: Christopher A Bottoms, Sherry Flint-Garcia and Michael D McMullen
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S28
  20. Functional genomics technologies that measure genome expression at a global scale are accelerating biological knowledge discovery. Generating these high throughput datasets is relatively easy compared to the d...

    Authors: Prashanti Manda, McKinley G Freeman, Susan M Bridges, TJ Jankun-Kelly, Bindu Nanduri, Fiona M McCarthy and Shane C Burgess
    Citation: BMC Bioinformatics 2010 11(Suppl 6):S29

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