Volume 11 Supplement 6
Proceedings of the Seventh Annual MCBIOS Conference. Bioinformatics: Systems, Biology, Informatics and Computation
Proceedings
Edited by Jonathan D Wren (Senior Editor), Dan Berleant, Susan M Bridges, Doris M Kupfer and Edward J Perkins
Seventh Annual MCBIOS Conference. Bioinformatics: Systems, Biology, Informatics and Computation. Go to conference site.
Jonesboro, AR, USA19-20 February 2010
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Citation: BMC Bioinformatics 2010 11(Suppl 6):S1
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Applying internal coordinate mechanics to model the interactions between 8R-lipoxygenase and its substrate
Lipoxygenases (LOX) play pivotal roles in the biosynthesis of leukotrienes and other biologically active potent signalling compounds. Developing inhibitors for LOX is of high interest to researchers. Modelling...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S2 -
Assessing constancy of substitution rates in viruses over evolutionary time
Phylogenetic analyses reveal probable patterns of divergence of present day organisms from common ancestors. The points of divergence of lineages can be dated if a corresponding historical or fossil record exi...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S3 -
An FDA bioinformatics tool for microbial genomics research on molecular characterization of bacterial foodborne pathogens using microarrays
Advances in microbial genomics and bioinformatics are offering greater insights into the emergence and spread of foodborne pathogens in outbreak scenarios. The Food and Drug Administration (FDA) has developed ...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S4 -
The EDKB: an established knowledge base for endocrine disrupting chemicals
Endocrine disruptors (EDs) and their broad range of potential adverse effects in humans and other animals have been a concern for nearly two decades. Many putative EDs are widely used in commercial products re...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S5 -
Two new ArrayTrack libraries for personalized biomedical research
Recent advances in high-throughput genotyping technology are paving the way for research in personalized medicine and nutrition. However, most of the genetic markers identified from association studies account...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S6 -
PEPPI: a peptidomic database of human protein isoforms for proteomics experiments
Protein isoform generation, which may derive from alternative splicing, genetic polymorphism, and posttranslational modification, is an essential source of achieving molecular diversity by eukaryotic cells. Pr...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S7 -
Identification of diagnostic subnetwork markers for cancer in human protein-protein interaction network
Finding reliable gene markers for accurate disease classification is very challenging due to a number of reasons, including the small sample size of typical clinical data, high noise in gene expression measure...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S8 -
Analysis of Bovine Viral Diarrhea Viruses-infected monocytes: identification of cytopathic and non-cytopathic biotype differences
Bovine Viral Diarrhea Virus (BVDV) infection is widespread in cattle worldwide, causing important economic losses. Pathogenesis of the disease caused by BVDV is complex, as each BVDV strain has two biotypes: n...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S9 -
Evaluation of gene expression data generated from expired Affymetrix GeneChip® microarrays using MAQC reference RNA samples
The Affymetrix GeneChip® system is a commonly used platform for microarray analysis but the technology is inherently expensive. Unfortunately, changes in experimental planning and execution, such as the unavailab...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S10 -
Mixed reality simulation of rasping procedure in artificial cervical disc replacement (ACDR) surgery
Until quite recently spinal disorder problems in the U.S. have been operated by fusing cervical vertebrae instead of replacement of the cervical disc with an artificial disc. Cervical disc replacement is a rec...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S11 -
Enzyme structure dynamics of xylanase I from Trichoderma longibrachiatum
Enzyme dynamics has recently been shown to be crucial for structure-function relationship. Among various structure dynamics analysis platforms, HDX (hydrogen deuterium exchange) mass spectrometry stands out as...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S12 -
Quail Genomics: a knowledgebase for Northern bobwhite
The Quail Genomics knowledgebase (http://​www.​quailgenomics.​info) has been initiated to share and develop functional genomic data for Northern bobwhite ...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S13 -
Discovering gene functional relationships using FAUN (Feature Annotation Using Nonnegative matrix factorization)
Searching the enormous amount of information available in biomedical literature to extract novel functional relationships among genes remains a challenge in the field of bioinformatics. While numerous (softwar...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S14 -
Next generation models for storage and representation of microbial biological annotation
Traditional genome annotation systems were developed in a very different computing era, one where the World Wide Web was just emerging. Consequently, these systems are built as centralized black boxes focused ...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S15 -
HPIDB - a unified resource for host-pathogen interactions
Protein-protein interactions (PPIs) play a crucial role in initiating infection in a host-pathogen system. Identification of these PPIs is important for understanding the underlying biological mechanism of inf...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S16 -
Promoter prediction in E. coli based on SIDD profiles and Artificial Neural Networks
One of the major challenges in biology is the correct identification of promoter regions. Computational methods based on motif searching have been the traditional approach taken. Recent studies have shown that...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S17 -
Phylometrics: a pipeline for inferring phylogenetic trees from a sequence relationship network perspective
Comparative sequence analysis of the 16S rRNA gene is frequently used to characterize the microbial diversity of environmental samples. However, sequence similarities do not always imply functional or evolutio...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S18 -
Time lagged information theoretic approaches to the reverse engineering of gene regulatory networks
A number of models and algorithms have been proposed in the past for gene regulatory network (GRN) inference; however, none of them address the effects of the size of time-series microarray expression data in ...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S19 -
A framework for automated enrichment of functionally significant inverted repeats in whole genomes
RNA transcripts from genomic sequences showing dyad symmetry typically adopt hairpin-like, cloverleaf, or similar structures that act as recognition sites for proteins. Such structures often are the precursors...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S20 -
A predictive model for secondary RNA structure using graph theory and a neural network
Determining the secondary structure of RNA from the primary structure is a challenging computational problem. A number of algorithms have been developed to predict the secondary structure from the primary stru...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S21 -
Comparative genome analysis of PHB gene family reveals deep evolutionary origins and diverse gene function
PHB (Prohibitin) gene family is involved in a variety of functions important for different biological processes. PHB genes are ubiquitously present in divergent species from prokaryotes to eukaryotes. Human PH...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S22 -
Lesion detection in demoscopy images with novel density-based and active contour approaches
Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. Automated assessment tools for dermoscopy images have become an important field of research...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S23 -
Dynamics of protofibril elongation and association involved in Aβ42 peptide aggregation in Alzheimer’s disease
The aggregates of a protein called, ‘Aβ’ found in brains of Alzheimer’s patients are strongly believed to be the cause for neuronal death and cognitive decline. Among the different forms of Aβ aggregates, smal...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S24 -
Integrated database for identifying candidate genes for Aspergillus flavus resistance in maize
Aspergillus flavus Link:Fr, an opportunistic fungus that produces aflatoxin, is pathogenic to maize and other oilseed crops. Aflatoxin is a potent carcinogen, and its presence markedly reduces the value of grain....
Citation: BMC Bioinformatics 2010 11(Suppl 6):S25 -
Analysis of density based and fuzzy c-means clustering methods on lesion border extraction in dermoscopy images
Computer-aided segmentation and border detection in dermoscopic images is one of the core components of diagnostic procedures and therapeutic interventions for skin cancer. Automated assessment tools for dermo...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S26 -
Constructing non-stationary Dynamic Bayesian Networks with a flexible lag choosing mechanism
Dynamic Bayesian Networks (DBNs) are widely used in regulatory network structure inference with gene expression data. Current methods assumed that the underlying stochastic processes that generate the gene exp...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S27 -
IView: introgression library visualization and query tool
An introgression library is a family of near-isogenic lines in a common genetic background, each of which carries one or more genomic regions contributed by a donor genome. Near-isogenic lines are powerful gen...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S28 -
GOModeler- A tool for hypothesis-testing of functional genomics datasets
Functional genomics technologies that measure genome expression at a global scale are accelerating biological knowledge discovery. Generating these high throughput datasets is relatively easy compared to the d...
Citation: BMC Bioinformatics 2010 11(Suppl 6):S29
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Citation Impact 2023
Journal Impact Factor: 2.9
5-year Journal Impact Factor: 3.6
Source Normalized Impact per Paper (SNIP): 0.821
SCImago Journal Rank (SJR): 1.005
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