Volume 12 Supplement 5

Selected articles from the IEEE International Conference on Bioinformatics and Biomedicine 2010

Proceedings

Edited by Stephen Tsui and Limsoon Wong

IEEE International Conference on Bioinformatics and Biomedicine 2010. Go to conference site.

Hong Kong, PR China18-21 December 2010

The BioAssay network and its implications to future therapeutic discovery

Despite intense investment growth and technology development, there is an observed bottleneck in drug discovery and development over the past decade. NIH started the Molecular Libraries Initiative (MLI) in 200...

Authors: Jintao Zhang, Gerald H Lushington and Jun Huan

Citation: BMC Bioinformatics 2011 12(Suppl 5):S1

Content type: Proceedings Published on: 27 July 2011
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Detection of splicing events and multiread locations from RNA-seq data based on a geometric-tail (GT) distribution of intron length

RNA sequencing (RNA-seq) measures gene expression levels and permits splicing analysis. Many existing aligners are capable of mapping millions of sequencing reads onto a reference genome. For reads that can be...

Authors: Shao-Ke Lou, Jing-Woei Li, Hao Qin, Aldrin Kay-Yuen Yim, Leung-Yau Lo, Bing Ni, Kwong-Sak Leung, Stephen Kwok-Wing Tsui and Ting-Fung Chan

Citation: BMC Bioinformatics 2011 12(Suppl 5):S2

Content type: Proceedings Published on: 27 July 2011
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Integrated analysis of the heterogeneous microarray data

As the magnitude of the experiment increases, it is common to combine various types of microarrays such as paired and non-paired microarrays from different laboratories or hospitals. Thus, it is important to a...

Authors: Sung Gon Yi and Taesung Park

Citation: BMC Bioinformatics 2011 12(Suppl 5):S3

Content type: Proceedings Published on: 27 July 2011
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SNP and gene networks construction and analysis from classification of copy number variations data

Detection of genomic DNA copy number variations (CNVs) can provide a complete and more comprehensive view of human disease. It is interesting to identify and represent relevant CNVs from a genome-wide data due...

Authors: Yang Liu, Yiu Fai Lee and Michael K Ng

Citation: BMC Bioinformatics 2011 12(Suppl 5):S4

Content type: Proceedings Published on: 27 July 2011
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Unsupervised fuzzy pattern discovery in gene expression data

Discovering patterns from gene expression levels is regarded as a classification problem when tissue classes of the samples are given and solved as a discrete-data problem by discretizing the expression levels...

Authors: Gene PK Wu, Keith CC Chan and Andrew KC Wong

Citation: BMC Bioinformatics 2011 12(Suppl 5):S5

Content type: Proceedings Published on: 27 July 2011
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A robust approach to optimizing multi-source information for enhancing genomics retrieval performance

The users desire to be provided short, specific answers to questions and put them in context by linking original sources from the biomedical literature. Through the use of information retrieval technologies, i...

Authors: Qinmin Hu, Jimmy Xiangji Huang and Jun Miao

Citation: BMC Bioinformatics 2011 12(Suppl 5):S6

Content type: Proceedings Published on: 27 July 2011
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Exploring matrix factorization techniques for significant genes identification of Alzheimer’s disease microarray gene expression data

The wide use of high-throughput DNA microarray technology provide an increasingly detailed view of human transcriptome from hundreds to thousands of genes. Although biomedical researchers typically design micr...

Authors: Wei Kong, Xiaoyang Mou and Xiaohua Hu

Citation: BMC Bioinformatics 2011 12(Suppl 5):S7

Content type: Proceedings Published on: 27 July 2011
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Promoting ranking diversity for genomics search with relevance-novelty combined model

In the biomedical domain, the desired information of a question (query) asked by biologists usually is a list of a certain type of entities covering different aspects that are related to the question, such as ...

Authors: Xiaoshi Yin, Zhoujun Li, Jimmy Xiangji Huang and Xiaohua Hu

Citation: BMC Bioinformatics 2011 12(Suppl 5):S8

Content type: Proceedings Published on: 27 July 2011
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Selected articles from the IEEE International Conference on Bioinformatics and Biomedicine 2010

Proceedings

The BioAssay network and its implications to future therapeutic discovery

Detection of splicing events and multiread locations from RNA-seq data based on a geometric-tail (GT) distribution of intron length

Integrated analysis of the heterogeneous microarray data

SNP and gene networks construction and analysis from classification of copy number variations data

Unsupervised fuzzy pattern discovery in gene expression data

A robust approach to optimizing multi-source information for enhancing genomics retrieval performance

Exploring matrix factorization techniques for significant genes identification of Alzheimer’s disease microarray gene expression data

Promoting ranking diversity for genomics search with relevance-novelty combined model

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