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Volume 13 Supplement 2

Proceedings from the Great Lakes Bioinformatics Conference 2011


Edited by Robert A Colvin and Jundong Liu

Great Lakes Bioinformatics Conference 2011. Go to conference site.

Athens, OH, USA2-4 May 2011

  1. Authors: Robert A Colvin and Jundong Liu
    Citation: BMC Bioinformatics 2012 13(Suppl 2):I1
  2. Current network-based microarray analysis uses the information of interactions among concerned genes/gene products, but still considers each gene expression individually. We propose an organized knowledge-supe...

    Authors: Xiaogang Wu, Hui Huang, Madhankumar Sonachalam, Sina Reinhard, Jeffrey Shen, Ragini Pandey and Jake Y Chen
    Citation: BMC Bioinformatics 2012 13(Suppl 2):S1
  3. RNA polymerase II (PolII) is essential in gene transcription and ChIP-seq experiments have been used to study PolII binding patterns over the entire genome. However, since PolII enriched regions in the genome ...

    Authors: Zhi Han, Lu Tian, Thierry Pécot, Tim Huang, Raghu Machiraju and Kun Huang
    Citation: BMC Bioinformatics 2012 13(Suppl 2):S2
  4. The DNA binding domain of HMG proteins is known to be important in many diseases, with the Sox sub-family of HMG proteins of particular significance. Numerous natural variants in HMG proteins are associated wi...

    Authors: Jeremy W Prokop, Thomas C Leeper, Zhong-Hui Duan and Amy Milsted
    Citation: BMC Bioinformatics 2012 13(Suppl 2):S3
  5. Results of high throughput experiments can be challenging to interpret. Current approaches have relied on bulk processing the set of expression levels, in conjunction with easily obtained external evidence, su...

    Authors: Fernando Farfán, Jun Ma, Maureen A Sartor, George Michailidis and Hosagrahar V Jagadish
    Citation: BMC Bioinformatics 2012 13(Suppl 2):S4
  6. The T box riboswitch controls bacterial transcription by structurally responding to tRNA aminoacylation charging ratios. Knowledge of the thermodynamic stability difference between two competing structural ele...

    Authors: Franziska Jentzsch and Jennifer V Hines
    Citation: BMC Bioinformatics 2012 13(Suppl 2):S5
  7. Predisposition to complex diseases is explained in part by genetic variation, and complex diseases are frequently comorbid, consistent with pleiotropic genetic variation influencing comorbidity. Genome Wide As...

    Authors: Richard C McEachin, Keerthi S Sannareddy, James D Cavalcoli, Alla Karnovsky, Jacqueline M Vink and Maureen A Sartor
    Citation: BMC Bioinformatics 2012 13(Suppl 2):S8
  8. Modern pyrosequencing techniques make it possible to study complex bacterial populations, such as 16S rRNA, directly from environmental or clinical samples without the need for laboratory purification. Alignment ...

    Authors: Adam Hughes, Yang Ruan, Saliya Ekanayake, Seung-Hee Bae, Qunfeng Dong, Mina Rho, Judy Qiu and Geoffrey Fox
    Citation: BMC Bioinformatics 2012 13(Suppl 2):S9
  9. As context is important to gene expression, so is the preprocessing of microarray to transcriptomics. Microarray data suffers from several normalization and significance problems. Arbitrary fold change (FC) cu...

    Authors: Mark R Dalman, Anthony Deeter, Gayathri Nimishakavi and Zhong-Hui Duan
    Citation: BMC Bioinformatics 2012 13(Suppl 2):S11
  10. Retrotransposons are mobile DNA elements that spread through genomes via the action of element-encoded reverse transcriptases. They are ubiquitous constituents of most eukaryotic genomes, especially those of h...

    Authors: Lauren S Mogil, Kamil Slowikowski and Howard M Laten
    Citation: BMC Bioinformatics 2012 13(Suppl 2):S13

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