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Volume 16 Supplement 5

Selected articles from the 10th International Symposium on Bioinformatics Research and Applications (ISBRA-14): Bioinformatics

Proceedings

Edited by Min Li, Jianxin Wang and Fangxiang Wu

Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. Articles have been through the journal's standard peer review process. The Supplement Editors declare that they have no competing interests.

10th International Symposium on Bioinformatics Research and Applications (ISBRA-14).

Zhangjiajie, China28-30 June 2014

Image from Sun et al., BMC Bioinformatics 2015, 16(Suppl 5):S1.

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  2. With the rapid development of high-throughput technologies, researchers can sequence the whole metagenome of a microbial community sampled directly from the environment. The assignment of these metagenomic rea...

    Authors: Ruichang Zhang, Zhanzhan Cheng, Jihong Guan and Shuigeng Zhou
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  3. Large-scale cancer genomic projects are providing lots of data on genomic, epigenomic and gene expression aberrations in many cancer types. One key challenge is to detect functional driver pathways and to filt...

    Authors: Hao Wu, Lin Gao, Feng Li, Fei Song, Xiaofei Yang and Nikola Kasabov
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  4. Progressive sequence alignment is one of the most commonly used method for multiple sequence alignment. Roughly speaking, the method first builds a guide tree, and then aligns the sequences progressively accor...

    Authors: Qing Zhan, Yongtao Ye, Tak-Wah Lam, Siu-Ming Yiu, Yadong Wang and Hing-Fung Ting
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  6. Systems approaches to studying drug-side-effect (drug-SE) associations are emerging as an active research area for both drug target discovery and drug repositioning. However, a comprehensive drug-SE associatio...

    Authors: Rong Xu and QuanQiu Wang
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  7. We consider the emerging problem of comparing the similarity between (unlabeled) pedigrees. More specifically, we focus on the simplest pedigrees, namely, the 2-generation pedigrees. We show that the isomorphi...

    Authors: Haitao Jiang, Guohui Lin, Weitian Tong, Daming Zhu and Binhai Zhu
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  8. Based on the next generation genome sequencing technologies, a variety of biological applications are developed, while alignment is the first step once the sequencing reads are obtained. In recent years, many ...

    Authors: Xiaoqing Peng, Jianxin Wang, Zhen Zhang, Qianghua Xiao, Min Li and Yi Pan
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  9. Identifying segments in the genome of different individuals that are identical-by-descent (IBD) is a fundamental element of genetics. IBD data is used for numerous applications including demographic inference,...

    Authors: Danny S Park, Yael Baran, Farhad Hormozdiari, Celeste Eng, Dara G Torgerson, Esteban G Burchard and Noah Zaitlen
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  10. Epigenetic alterations are known to correlate with changes in gene expression among various diseases including cancers. However, quantitative models that accurately predict the up or down regulation of gene ex...

    Authors: Jeffery Li, Travers Ching, Sijia Huang and Lana X Garmire
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  11. Metabolomics is the study of small molecules, called metabolites, of a cell, tissue or organism. It is of particular interest as endogenous metabolites represent the phenotype resulting from gene expression. A...

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