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Volume 19 Supplement 15

Proceedings from the 12th International BBCC conference

Research

Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Naples, Italy18 - 20 December 2017

Edited by Anna Marabotti, Claudia Angelini and Angelo Facchiano.

Conference website

  1. Study of macromolecular assemblies is fundamental to understand functions in cells. X-ray crystallography is the most common technique to solve their 3D structure at atomic resolution. In a crystal, however, b...

    Authors: Katarina Elez, Alexandre M. J. J. Bonvin and Anna Vangone
    Citation: BMC Bioinformatics 2018 19(Suppl 15):438
  2. Spaced-seeds, i.e. patterns in which some fixed positions are allowed to be wild-cards, play a crucial role in several bioinformatics applications involving substrings counting and indexing, by often providing...

    Authors: Samuele Girotto, Matteo Comin and Cinzia Pizzi
    Citation: BMC Bioinformatics 2018 19(Suppl 15):441
  3. Severity gradation of missense mutations is a big challenge for exome annotation. Predictors of deleteriousness that are most frequently used to filter variants found by next generation sequencing, produce qua...

    Authors: Chiara Cimmaruta, Valentina Citro, Giuseppina Andreotti, Ludovica Liguori, Maria Vittoria Cubellis and Bruno Hay Mele
    Citation: BMC Bioinformatics 2018 19(Suppl 15):433
  4. Pan-genome approaches afford the discovery of homology relations in a set of genomes, by determining how some gene families are distributed among a given set of genomes. The retrieval of a complete gene distri...

    Authors: Vincenzo Bonnici, Rosalba Giugno and Vincenzo Manca
    Citation: BMC Bioinformatics 2018 19(Suppl 15):437
  5. microRNAs act as regulators of gene expression interacting with their gene targets. Current bioinformatics services, such as databases of validated miRNA-target interactions and prediction tools, usually provi...

    Authors: Antonino Fiannaca, Massimo La Rosa, Laura La Paglia and Alfonso Urso
    Citation: BMC Bioinformatics 2018 19(Suppl 15):434
  6. Microbes are essentail components of all ecosystems because they drive many biochemical processes and act as primary producers. In freshwater ecosystems, the biodiversity in and the composition of microbial co...

    Authors: Theodor Sperlea, Stefan Füser, Jens Boenigk and Dominik Heider
    Citation: BMC Bioinformatics 2018 19(Suppl 15):440
  7. “Omics” approaches may provide useful information for a deeper understanding of speciation events, diversification and function innovation. This can be achieved by investigating the molecular similarities at s...

    Authors: Luca Ambrosino, Valentino Ruggieri, Hamed Bostan, Marco Miralto, Nicola Vitulo, Mohamed Zouine, Amalia Barone, Mondher Bouzayen, Luigi Frusciante, Mario Pezzotti, Giorgio Valle and Maria Luisa Chiusano
    Citation: BMC Bioinformatics 2018 19(Suppl 15):435
  8. It is well-known that glioblastoma contains self-renewing, stem-like subpopulation with the ability to sustain tumor growth. These cells – called cancer stem-like cells – share certain phenotypic characteristi...

    Authors: Giulia Fiscon, Federica Conte and Paola Paci
    Citation: BMC Bioinformatics 2018 19(Suppl 15):436
  9. The study of cell metabolism is becoming central in several fields such as biotechnology, evolution/adaptation and human disease investigations. Here we present CiliateGEM, the first metabolic network reconstr...

    Authors: Alessio Mancini, Filmon Eyassu, Maxwell Conway, Annalisa Occhipinti, Pietro Liò, Claudio Angione and Sandra Pucciarelli
    Citation: BMC Bioinformatics 2018 19(Suppl 15):442
  10. Environmental metagenomics is a challenging approach that is exponentially spreading in the scientific community to investigate taxonomic diversity and possible functions of the biological components. The mass...

    Authors: M. Tangherlini, M. Miralto, C. Colantuono, M. Sangiovanni, A. Dell’ Anno, C. Corinaldesi, R. Danovaro and M. L. Chiusano
    Citation: BMC Bioinformatics 2018 19(Suppl 15):443

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