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Volume 21 Supplement 17

Selected papers from the 3rd International Workshop on Computational Methods for the Immune System Function (CMISF 2019)


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. Supplement Editors did not handle peer review on any articles that they have co-authored. The Supplement Editors declare that they have no other competing interests.

San Diego, CA, USA18-21 November 2019

Edited by Francesco Pappalardo, Giulia Russo, Marzio Pennisi and Pedro Reche

Conference website

  1. The 3rd edition of the computational methods for the immune system function workshop has been held in San Diego, CA, in conjunction with the IEEE International Conference on Bioinformatics and Biomedicine (BIB...

    Authors: Francesco Pappalardo, Giulia Russo and Pedro A. Reche
    Citation: BMC Bioinformatics 2020 21(Suppl 17):546
  2. SARS-CoV-2 is a severe respiratory infection that infects humans. Its outburst entitled it as a pandemic emergence. To get a grip on this outbreak, specific preventive and therapeutic interventions are urgentl...

    Authors: Giulia Russo, Marzio Pennisi, Epifanio Fichera, Santo Motta, Giuseppina Raciti, Marco Viceconti and Francesco Pappalardo
    Citation: BMC Bioinformatics 2020 21(Suppl 17):527
  3. In 2018, about 10 million people were found infected by tuberculosis, with approximately 1.2 million deaths worldwide. Despite these numbers have been relatively stable in recent years, tuberculosis is still c...

    Authors: Giulia Russo, Giuseppe Sgroi, Giuseppe Alessandro Parasiliti Palumbo, Marzio Pennisi, Miguel A. Juarez, Pere-Joan Cardona, Santo Motta, Kenneth B. Walker, Epifanio Fichera, Marco Viceconti and Francesco Pappalardo
    Citation: BMC Bioinformatics 2020 21(Suppl 17):458
  4. The aim of a recent research project was the investigation of the mechanisms involved in the onset of type 2 diabetes in the absence of familiarity. This has led to the development of a computational model tha...

    Authors: Paola Stolfi, Ilaria Valentini, Maria Concetta Palumbo, Paolo Tieri, Andrea Grignolio and Filippo Castiglione
    Citation: BMC Bioinformatics 2020 21(Suppl 17):508
  5. We previously introduced PCPS (Proteasome Cleavage Prediction Server), a web-based tool to predict proteasome cleavage sites using n-grams. Here, we evaluated the ability of PCPS immunoproteasome cleavage model t...

    Authors: Marta Gomez-Perosanz, Alvaro Ras-Carmona, Esther M. Lafuente and Pedro A. Reche
    Citation: BMC Bioinformatics 2020 21(Suppl 17):484
  6. Prediction of patient outcome in medical intensive care units (ICU) may help for development and investigation of early interventional strategies. Several ICU scoring systems have been developed and are used t...

    Authors: Ping Zhang, Tegan Roberts, Brent Richards and Luke J. Haseler
    Citation: BMC Bioinformatics 2020 21(Suppl 17):481
  7. An effective yellow fever (YF) vaccine has been available since 1937. Nevertheless, questions regarding its use remain poorly understood, such as the ideal dose to confer immunity against the disease, the need...

    Authors: Carla Rezende Barbosa Bonin, Guilherme Côrtes Fernandes, Reinaldo de Menezes Martins, Luiz Antonio Bastos Camacho, Andréa Teixeira-Carvalho, Licia Maria Henrique da Mota, Sheila Maria Barbosa de Lima, Ana Carolina Campi-Azevedo, Olindo Assis Martins-Filho, Rodrigo Weber dos Santos and Marcelo Lobosco
    Citation: BMC Bioinformatics 2020 21(Suppl 17):551
  8. The immune checkpoint receptor programmed cell death protein I (PD-1) has been identified as a key target in immunotherapy. PD-1 reduces the risk of autoimmunity by inducing apoptosis in antigen-specific T cel...

    Authors: Bernhard Roither, Chris Oostenbrink and Wolfgang Schreiner
    Citation: BMC Bioinformatics 2020 21(Suppl 17):557
  9. Multiple Sclerosis (MS) represents nowadays in Europe the leading cause of non-traumatic disabilities in young adults, with more than 700,000 EU cases. Although huge strides have been made over the years, MS e...

    Authors: Simone Pernice, Laura Follia, Alessandro Maglione, Marzio Pennisi, Francesco Pappalardo, Francesco Novelli, Marinella Clerico, Marco Beccuti, Francesca Cordero and Simona Rolla
    Citation: BMC Bioinformatics 2020 21(Suppl 17):550
  10. The STriTuVaD project, funded by Horizon 2020, aims to test through a Phase IIb clinical trial one of the most advanced therapeutic vaccines against tuberculosis. As part of this initiative, we have developed ...

    Authors: Miguel A. Juárez, Marzio Pennisi, Giulia Russo, Dimitrios Kiagias, Cristina Curreli, Marco Viceconti and Francesco Pappalardo
    Citation: BMC Bioinformatics 2020 21(Suppl 17):449

Part 2 of this supplement is available here.

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