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Volume 7 Supplement 5
Edited by Shoba Ranganathan, Martti Tammi, Michael Gribskov, Tin Wee Tan
International Conference in Bioinformatics - InCoB2006.
New Delhi, India
18-20 December 2006
Introduction
In 1998, the Asia Pacific Bioinformatics Network (APBioNet), Asia's oldest bioinformatics organisation was set up to champion the advancement of bioinformatics in the Asia Pacific. By 2002, APBioNet was able t...
BMC Bioinformatics 2006 7(Suppl 5):S1
Published on: 18 December 2006
Proceedings
Automatic annotation of sequenced eukaryotic genomes integrates a combination of methodologies such as ab-initio methods and alignment of homologous genes and/or proteins. For example, annotation of the zebrafish...
BMC Bioinformatics 2006 7(Suppl 5):S2
Published on: 18 December 2006
Proceedings
Determination of the subcellular location of a protein is essential to understanding its biochemical function. This information can provide insight into the function of hypothetical or novel proteins. These da...
BMC Bioinformatics 2006 7(Suppl 5):S3
Published on: 18 December 2006
Proceedings
Antigenic diversity in dengue virus strains has been studied, but large-scale and detailed systematic analyses have not been reported. In this study, we report a bioinformatics method for analyzing viral antig...
BMC Bioinformatics 2006 7(Suppl 5):S4
Published on: 18 December 2006
Proceedings
In recent times, there has been an exponential rise in the number of protein structures in databases e.g. PDB. So, design of fast algorithms capable of querying such databases is becoming an increasingly impor...
BMC Bioinformatics 2006 7(Suppl 5):S5
Published on: 18 December 2006
Proceedings
Knowledge of protein domain boundaries is critical for the characterisation and understanding of protein function. The ability to identify domains without the knowledge of the structure – by using sequence inf...
BMC Bioinformatics 2006 7(Suppl 5):S6
Published on: 18 December 2006
Proceedings
Pemphigus vulgaris (PV) is a severe autoimmune blistering skin disorder that is strongly associated with major histocompatibility complex class II alleles DRB1*0402 and DQB1*0503. The target antigen of PV, des...
BMC Bioinformatics 2006 7(Suppl 5):S7
Published on: 18 December 2006
Proceedings
Mammalian antimicrobial peptides (AMPs) are effectors of the innate immune response. A multitude of signals coming from pathways of mammalian pathogen/pattern recognition receptors and other proteins affect th...
BMC Bioinformatics 2006 7(Suppl 5):S8
Published on: 18 December 2006
Proceedings
A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is to identify transcriptional units, operons ...
BMC Bioinformatics 2006 7(Suppl 5):S9
Published on: 18 December 2006
Review
Grid computing has great potential to become a standard cyberinfrastructure for life sciences which often require high-performance computing and large data handling which exceeds the computing capacity of a si...
BMC Bioinformatics 2006 7(Suppl 5):S10
Published on: 18 December 2006
Proceedings
Biomedical named entity recognition (Bio-NER) is a challenging problem because, in general, biomedical named entities of the same category (e.g., proteins and genes) do not follow one standard nomenclature. Th...
BMC Bioinformatics 2006 7(Suppl 5):S11
Published on: 18 December 2006
Proceedings
Whole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing initiatives of human and model organisms are targete...
BMC Bioinformatics 2006 7(Suppl 5):S12
Published on: 18 December 2006
Proceedings
Metal-binding proteins play important roles in structural stability, signaling, regulation, transport, immune response, metabolism control, and metal homeostasis. Because of their functional and sequence diver...
BMC Bioinformatics 2006 7(Suppl 5):S13
Published on: 18 December 2006
Proceedings
Caspases belong to a class of cysteine proteases which function as critical effectors in apoptosis and inflammation by cleaving substrates immediately after unique sites. Prediction of such cleavage sites will...
BMC Bioinformatics 2006 7(Suppl 5):S14
Published on: 18 December 2006
Proceedings
Recent advances and automation in DNA sequencing technology has created a vast amount of DNA sequence data. This increasing growth of sequence data demands better and efficient analysis methods. Identifying ge...
BMC Bioinformatics 2006 7(Suppl 5):S15
Published on: 18 December 2006
The Erratum to this article has been published in BMC Bioinformatics 2007 8:241
Proceedings
Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell, experimentally or computationally, is an ...
BMC Bioinformatics 2006 7(Suppl 5):S16
Published on: 18 December 2006
Proceedings
Defensins are antimicrobial peptides of innate immunity functioning by non-specific binding to anionic phospholipids in bacterial membranes. Their cationicity, amphipathicity and ability to oligomerize are con...
BMC Bioinformatics 2006 7(Suppl 5):S17
Published on: 18 December 2006
Proceedings
Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein interaction networks of Drosophila melanogast...
BMC Bioinformatics 2006 7(Suppl 5):S18
Published on: 18 December 2006
Proceedings
Protein-protein interaction (PPI) databases have become a major resource for investigating biological networks and pathways in cells. A number of publicly available repositories for human PPIs are currently av...
BMC Bioinformatics 2006 7(Suppl 5):S19
Published on: 18 December 2006
Proceedings
The accurate prediction of a comprehensive set of messenger RNAs (targets) regulated by animal microRNAs (miRNAs) remains an open problem. In particular, the prediction of targets that do not possess evolution...
BMC Bioinformatics 2006 7(Suppl 5):S20
Published on: 18 December 2006
