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  • Erratum
  • Open Access

Erratum to: Guide Picker is a comprehensive design tool for visualizing and selecting guides for CRISPR experiments

  • 1Email author,
  • 1,
  • 1,
  • 1,
  • 1,
  • 1,
  • 1 and
  • 1
Contributed equally
BMC BioinformaticsBMC series – open, inclusive and trusted201718:202

https://doi.org/10.1186/s12859-017-1618-8

  • Received: 28 March 2017
  • Accepted: 29 March 2017
  • Published:

The original article was published in BMC Bioinformatics 2017 18:167

Erratum

Following publication of this article [1], it has come to our attention that a caption for figure 6 is incorrect. Presently, it reads “Fig. 6 Designing a Tiling Experiment with Guide Picker. a First, guides are plotted along the length of the MCDS using percent peptide on the x-axis. The y-axis is set to Doench 2016 Positionless. b Filtering guides to a strict score threshold (e.g. < 55) offers a panel of guides that still target along the full length of the MCDS. c The right-hand plot can then be set and filtered according to other guide parameters, such as GC (30–70%) content and Hsu 2013 ( < 68) off-target scoring. d The guides in this range can then be highlighted to verify that this select group of guides still target along the full length of the MCDS in the left-hand plot”. However, the less than (<) symbols should be more than (>) symbols and the caption should read, “Fig. 6 Designing a Tiling Experiment with Guide Picker. a First, guides are plotted along the length of the MCDS using percent peptide on the x-axis. The y-axis is set to Doench 2016 Positionless. b Filtering guides to a strict score threshold (e.g. >55 ) offers a panel of guides that still target along the full length of the MCDS. c The right-hand plot can then be set and filtered according to other guide parameters, such as GC (30–70%) content and Hsu 2013 ( >68 ) off-target scoring. d The guides in this range can then be highlighted to verify that this select group of guides still target along the full length of the MCDS in the left-hand plot.”

Notes

Declarations

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
Desktop Genetics, Ltd., 28 Hanbury Street, London, E1 6QR, UK

Reference

  1. Hough S, Kancleris K, Brody L, Humphryes-Kirilov N, Wolanski J, Dunaway K, Ajetunmobi A, Dillard V. Guide Picker is a comprehensive design tool for visualizing and selecting guides for CRISPR experiments. BMC Bioinformatics. 2017;18:167. doi:10.1186/s12859-017-1581-4.View ArticlePubMedPubMed CentralGoogle Scholar

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