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Volume 12 Supplement 10

Proceedings of the Eighth Annual MCBIOS Conference. Computational Biology and Bioinformatics for a New Decade


Edited by Jonathan D Wren (senior editor), Doris M Kupfer, Edward J Perkins, Susan Bridges, Stephen Winters-Hilt, Mikhail G Dozmorov and Ulisses Braga-Neto

Eighth Annual MCBIOS Conference. Computational Biology and Bioinformatics for a New Decade. Go to conference site.

College Station, TX, USA1-2 April 2011

  1. Content type: Proceedings

    Genomic biomarkers play an increasing role in both preclinical and clinical application. Development of genomic biomarkers with microarrays is an area of intensive investigation. However, despite sustained and...

    Authors: Minjun Chen, Leming Shi, Reagan Kelly, Roger Perkins, Hong Fang and Weida Tong

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S3

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  2. Content type: Proceedings

    Each organ has a specific function in the body. “Organ-specificity” refers to differential expressions of the same gene across different organs. An organ-specific gene/protein is defined as a gene/protein whos...

    Authors: Fan Zhang and Jake Y Chen

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S4

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  3. Content type: Proceedings

    RNA-Seq is the recently developed high-throughput sequencing technology for profiling the entire transcriptome in any organism. It has several major advantages over current hybridization-based approach such as...

    Authors: Ying Wang, Noushin Ghaffari, Charles D Johnson, Ulisses M Braga-Neto, Hui Wang, Rui Chen and Huaijun Zhou

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S5

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  4. Content type: Proceedings

    Comparative network analysis aims to identify common subnetworks in biological networks. It can facilitate the prediction of conserved functional modules across different species and provide deep insights into...

    Authors: Xiaoning Qian, Sayed Mohammad Ebrahim Sahraeian and Byung-Jun Yoon

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S6

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  5. Content type: Proceedings

    Protein-protein interactions (PPIs) are a critical component for many underlying biological processes. A PPI network can provide insight into the mechanisms of these processes, as well as the relationships amo...

    Authors: Venkata-Swamy Martha, Zhichao Liu, Li Guo, Zhenqiang Su, Yanbin Ye, Hong Fang, Don Ding, Weida Tong and Xiaowei Xu

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S7

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  6. Content type: Proceedings

    Recent advances in genomics and proteomics have allowed us to study the nuances of the Warburg effect – a long-standing puzzle in cancer energy metabolism – at an unprecedented level of detail. While modern ne...

    Authors: Aleksandra A Markovets and Damir Herman

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S8

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  7. Content type: Proceedings

    Accumulation of gene mutations in cells is known to be responsible for tumor progression, driving it from benign states to malignant states. However, previous studies have shown that the detailed sequence of g...

    Authors: Mohammad Shahrokh Esfahani, Byung-Jun Yoon and Edward R Dougherty

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S9

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  8. Content type: Proceedings

    One of the most important goals of the mathematical modeling of gene regulatory networks is to alter their behavior toward desirable phenotypes. Therapeutic techniques are derived for intervention in terms of ...

    Authors: Noushin Ghaffari, Ivan Ivanov, Xiaoning Qian and Edward R Dougherty

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S10

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  9. Content type: Proceedings

    In all amyloid diseases, protein aggregates have been implicated fully or partly, in the etiology of the disease. Due to their significance in human pathologies, there have been unprecedented efforts towards p...

    Authors: Srisairam Achuthan, Bong Jae Chung, Preetam Ghosh, Vijayaraghavan Rangachari and Ashwin Vaidya

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S13

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  10. Content type: Proceedings

    Hypertension may increase tortuosity or twistedness of arteries. We applied a centerline extraction algorithm and tortuosity metric to magnetic resonance angiography (MRA) brain images to quantitatively measur...

    Authors: Karl T Diedrich, John A Roberts, Richard H Schmidt, Chang-Ki Kang, Zang-Hee Cho and Dennis L Parker

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S15

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  11. Content type: Proceedings

    Biology is rapidly becoming a data intensive, data-driven science. It is essential that data is represented and connected in ways that best represent its full conceptual content and allows both automated integ...

    Authors: Shelton D Griffith, Daniel J Quest, Thomas S Brettin and Robert W Cottingham

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S17

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  12. Content type: Proceedings

    Proteins search along the DNA for targets, such as transcription initiation sequences, according to one-dimensional diffusion, which is interrupted by micro- and macro-hopping events and intersegmental transfe...

    Authors: Michael L Mayo, Edward J Perkins and Preetam Ghosh

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S18

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  13. Content type: Proceedings

    Identification of transcription factors (TFs) responsible for modulation of differentially expressed genes is a key step in deducing gene regulatory pathways. Most current methods identify TFs by searching for...

    Authors: Sujoy Roy, Kevin Heinrich, Vinhthuy Phan, Michael W Berry and Ramin Homayouni

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S19

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  14. Content type: Proceedings

    Gene Regulatory Networks (GRNs) provide integrated views of gene interactions that control biological processes. Many public databases contain biological interactions extracted from experimentally validated li...

    Authors: Ying Li, Ping Gong, Edward J Perkins, Chaoyang Zhang and Nan Wang

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S20

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  15. Content type: Proceedings

    Nanopore transduction detection (NTD) offers prospects for a number of highly sensitive and discriminative applications, including: (i) single nucleotide polymorphism (SNP) detection; (ii) targeted DNA re-sequ...

    Authors: Stephen Winters-Hilt, Evenie Horton-Chao and Eric Morales

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S21

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  16. Content type: Proceedings

    It is commonly believed that including domain knowledge in a prediction model is desirable. However, representing and incorporating domain information in the learning process is, in general, a challenging prob...

    Authors: Xiaofei Nan, Gang Fu, Zhengdong Zhao, Sheng Liu, Ronak Y Patel, Haining Liu, Pankaj R Daga, Robert J Doerksen, Xin Dang, Yixin Chen and Dawn Wilkins

    Citation: BMC Bioinformatics 2011 12(Suppl 10):S22

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2018 Journal Metrics

  • Citation Impact
    2.511 - 2-year Impact Factor
    2.970 - 5-year Impact Factor
    0.855 - Source Normalized Impact per Paper (SNIP)
    1.374 - SCImago Journal Rank (SJR)


    Social Media Impact
    4446 mentions