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Volume 14 Supplement 9

Selected articles from the 8th International Symposium on Bioinformatics Research and Applications (ISBRA'12)

Methodology Articles

Edited by Russell Schwartz, Rajshekhar Sunderraman, Jianxin Wang and Alexander Zelikovsky

Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The content of the supplement is based on presentations made at ISBRA 2012, the conference was partially supported by U.S. NSF award IIS-1237310. Articles have undergone the journal’s standard peer-review process for supplements. The Supplement Editors declare that they have no competing interests.

8th International Symposium on Bioinformatics Research and Applications (ISBRA'12). Go to conference site.

Dallas, TX, USA21-23 May 2012

  1. High throughput parallel sequencing, RNA-Seq, has recently emerged as an appealing alternative to microarray in identifying differentially expressed genes (DEG) between biological groups. However, there still ...

    Authors: Xiao Xu, Yuanhao Zhang, Jennie Williams, Eric Antoniou, W Richard McCombie, Song Wu, Wei Zhu, Nicholas O Davidson, Paula Denoya and Ellen Li
    Citation: BMC Bioinformatics 2013 14(Suppl 9):S1
  2. Highly mutable RNA viruses exist in infected hosts as heterogeneous populations of genetically close variants known as quasispecies. Next-generation sequencing (NGS) allows for analysing a large number of vira...

    Authors: Pavel Skums, Nicholas Mancuso, Alexander Artyomenko, Bassam Tork, Ion Mandoiu, Yury Khudyakov and Alex Zelikovsky
    Citation: BMC Bioinformatics 2013 14(Suppl 9):S2
  3. We are focusing specifically on fast data analysis and retrieval in bioinformatics that will have a direct impact on the quality of human health and the environment. The exponential growth of data generated in...

    Authors: Bhanu Rekapalli, Paul Giblock and Christopher Reardon
    Citation: BMC Bioinformatics 2013 14(Suppl 9):S3
  4. Computational gene finding algorithms have proven their robustness in identifying genes in complete genomes. However, metagenomic sequencing has presented new challenges due to the incomplete and fragmented na...

    Authors: Achraf El Allali and John R Rose
    Citation: BMC Bioinformatics 2013 14(Suppl 9):S6

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