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Volume 16 Supplement 13

Proceedings of the 12th Annual MCBIOS Conference

Proceedings

Edited by Jonathan D Wren, Shraddah Thakkar, Ramin Homayouni, Donald J Johann and Mikhail G Dozmorov

Publication of this supplement has not been supported by sponsorhsip. Information about the source of funding for publication charges can be found in the individual articles. Articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

12th Annual MCBIOS Conference. Go to conference site.

Little Rock, AR, USA13-14 March 2015

  1. An accurate understanding of interactions among genes plays a major role in developing therapeutic intervention methods. Gene regulatory networks often contain a significant amount of uncertainty. The process ...

    Authors: Roozbeh Dehghannasiri, Byung-Jun Yoon and Edward R Dougherty
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S2

    The Erratum to this article has been published in BMC Bioinformatics 2015 16:410

  2. Most dynamical models for genomic networks are built upon two current methodologies, one process-based and the other based on Boolean-type networks. Both are problematic when it comes to experimental design pu...

    Authors: Daniel N Mohsenizadeh, Jianping Hua, Michael Bittner and Edward R Dougherty
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S3
  3. Drug repositioning is a cost-efficient and time-saving process to drug development compared to traditional techniques. A systematic method to drug repositioning is to identify candidate drug's gene expression ...

    Authors: Hui Huang, Thanh Nguyen, Sara Ibrahim, Sandeep Shantharam, Zongliang Yue and Jake Y Chen
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S4
  4. Dermoscopy is a highly effective and noninvasive imaging technique used in diagnosis of melanoma and other pigmented skin lesions. Many aspects of the lesion under consideration are defined in relation to the ...

    Authors: James Lemon, Sinan Kockara, Tansel Halic and Mutlu Mete
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S5
  5. Comprehensive capture of Adverse Events (AEs) is crucial for monitoring for side effects of a therapy while assessing efficacy. For cancer studies, the National Cancer Institute has developed the Common Termin...

    Authors: Alex Lencioni, Laura Hutchins, Sandy Annis, Wanchi Chen, Emre Ermisoglu, Zhidan Feng, Karen Mack, Kacie Simpson, Cheryl Lane and Umit Topaloglu
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S6
  6. It is understood that cancer is a clonal disease initiated by a single cell, and that metastasis, which is the spread of cancer from the primary site, is also initiated by a single cell. The seemingly natural ...

    Authors: Erich A Peterson, Michael A Bauer, Shweta S Chavan, Cody Ashby, Niels Weinhold, Christoph J Heuck, Gareth J Morgan and Donald J Johann
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S7
  7. Topic modelling is an active research field in machine learning. While mainly used to build models from unstructured textual data, it offers an effective means of data mining where samples represent documents,...

    Authors: Weizhong Zhao, James J Chen, Roger Perkins, Zhichao Liu, Weigong Ge, Yijun Ding and Wen Zou
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S8
  8. As the major histocompatibility complex (MHC), human leukocyte antigens (HLAs) are one of the most polymorphic genes in humans. Patients carrying certain HLA alleles may develop adverse drug reactions (ADRs) a...

    Authors: Heng Luo, Hao Ye, Hui Wen Ng, Leming Shi, Weida Tong, William Mattes, Donna Mendrick and Huixiao Hong
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S9
  9. Adapter trimming and removal of duplicate reads are common practices in next-generation sequencing pipelines. Sequencing reads ambiguously mapped to repetitive and low complexity regions can also be problemati...

    Authors: Mikhail G Dozmorov, Indra Adrianto, Cory B Giles, Edmund Glass, Stuart B Glenn, Courtney Montgomery, Kathy L Sivils, Lorin E Olson, Tomoaki Iwayama, Willard M Freeman, Christopher J Lessard and Jonathan D Wren
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S10
  10. A wealth of protein interaction data has become available in recent years, creating an urgent need for powerful analysis techniques. In this context, the problem of finding biologically meaningful corresponden...

    Authors: Jakob Dohrmann, Juris Puchin and Rahul Singh
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S11
  11. Maize, a crop of global significance, is vulnerable to a variety of biotic stresses resulting in economic losses. Fusarium verticillioides (teleomorph Gibberella moniliformis) is one of the key fungal pathogens o...

    Authors: Mansuck Kim, Huan Zhang, Charles Woloshuk, Won-Bo Shim and Byung-Jun Yoon
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S12
  12. The dimension and complexity of high-throughput gene expression data create many challenges for downstream analysis. Several approaches exist to reduce the number of variables with respect to small sample size...

    Authors: Behrouz Madahian, Sujoy Roy, Dale Bowman, Lih Y Deng and Ramin Homayouni
    Citation: BMC Bioinformatics 2015 16(Suppl 13):S13

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