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Volume 20 Supplement 25

Selected Papers from the Proceedings of the 2018 International Conference on Intelligent Computing (ICIC 2018) and Intelligent Computing and Biomedical Informatics (ICBI) 2018 conference: bioinformatics


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editor declares that they have no competing interests.

Wuhan and Shanghai, China15-18 August 2018, 3-4 November 2018

Edited by De-Shuang Huang

Conference website

  1. Cost-sensitive algorithm is an effective strategy to solve imbalanced classification problem. However, the misclassification costs are usually determined empirically based on user expertise, which leads to uns...

    Authors: Huijuan Lu, Yige Xu, Minchao Ye, Ke Yan, Zhigang Gao and Qun Jin
    Citation: BMC Bioinformatics 2019 20(Suppl 25):681
  2. In ab initio protein-structure predictions, a large set of structural decoys are often generated, with the requirement to select best five or three candidates from the decoys. The clustered central structures ...

    Authors: Hongjie Wu, Hongmei Huang, Weizhong Lu, Qiming Fu, Yijie Ding, Jing Qiu and Haiou Li
    Citation: BMC Bioinformatics 2019 20(Suppl 25):683
  3. RNA secondary structure prediction is an important issue in structural bioinformatics, and RNA pseudoknotted secondary structure prediction represents an NP-hard problem. Recently, many different machine-learn...

    Authors: Weizhong Lu, Ye Tang, Hongjie Wu, Hongmei Huang, Qiming Fu, Jing Qiu and Haiou Li
    Citation: BMC Bioinformatics 2019 20(Suppl 25):684
  4. Protein structure prediction has always been an important issue in bioinformatics. Prediction of the two-dimensional structure of proteins based on the hydrophobic polarity model is a typical non-deterministic...

    Authors: Hongjie Wu, Ru Yang, Qiming Fu, Jianping Chen, Weizhong Lu and Haiou Li
    Citation: BMC Bioinformatics 2019 20(Suppl 25):685
  5. Predicting miRNA-disease associations (MDAs) is time-consuming and expensive. It is imminent to improve the accuracy of prediction results. So it is crucial to develop a novel computing technology to predict n...

    Authors: Zhen Cui, Jin-Xing Liu, Ying-Lian Gao, Chun-Hou Zheng and Juan Wang
    Citation: BMC Bioinformatics 2019 20(Suppl 25):686
  6. Bamboo is a very important forest resource. However, the prolonged vegetative stages and uncertainty of flowering brings difficulties in bamboo flowers sampling. Until now, the flowering mechanism of bamboo is...

    Authors: Yulian Jiao, Qiutao Hu, Yan Zhu, Longfei Zhu, Tengfei Ma, Haiyong Zeng, Qiaolu Zang, Xuan Li and Xinchun Lin
    Citation: BMC Bioinformatics 2019 20(Suppl 25):687
  7. The occurrence of cotton pests and diseases has always been an important factor affecting the total cotton production. Cotton has a great dependence on environmental factors during its growth, especially clima...

    Authors: Qingxin Xiao, Weilu Li, Yuanzhong Kai, Peng Chen, Jun Zhang and Bing Wang
    Citation: BMC Bioinformatics 2019 20(Suppl 25):688
  8. Accurate identification of potential interactions between drugs and protein targets is a critical step to accelerate drug discovery. Despite many relative experimental researches have been done in the past dec...

    Authors: ShanShan Hu, Chenglin Zhang, Peng Chen, Pengying Gu, Jun Zhang and Bing Wang
    Citation: BMC Bioinformatics 2019 20(Suppl 25):689
  9. The association between BIN1 rs744373 variant and Alzheimer’s disease (AD) had been identified by genome-wide association studies (GWASs) as well as candidate gene studies in Caucasian populations. But in East...

    Authors: Zhifa Han, Tao Wang, Rui Tian, Wenyang Zhou, Pingping Wang, Peng Ren, Jian Zong, Yang Hu, Shuilin Jin and Qinghua Jiang
    Citation: BMC Bioinformatics 2019 20(Suppl 25):691
  10. 2′-O-methylation (2′-O-me or Nm) is a post-transcriptional RNA methylation modified at 2′-hydroxy, which is common in mRNAs and various non-coding RNAs. Previous studies revealed the significance of Nm in mult...

    Authors: Yiran Zhou, Qinghua Cui and Yuan Zhou
    Citation: BMC Bioinformatics 2019 20(Suppl 25):690
  11. Glaucoma is an irreversible eye disease caused by the optic nerve injury. Therefore, it usually changes the structure of the optic nerve head (ONH). Clinically, ONH assessment based on fundus image is one of t...

    Authors: Beiji Zou, Changlong Chen, Rongchang Zhao, Pingbo Ouyang, Chengzhang Zhu, Qilin Chen and Xuanchu Duan
    Citation: BMC Bioinformatics 2019 20(Suppl 25):693
  12. The interactions among proteins act as crucial roles in most cellular processes. Despite enormous effort put for identifying protein-protein interactions (PPIs) from a large number of organisms, existing first...

    Authors: Zhengwei Li, Ru Nie, Zhuhong You, Chen Cao and Jiashu Li
    Citation: BMC Bioinformatics 2019 20(Suppl 25):694
  13. Imbalanced datasets are commonly encountered in bioinformatics classification problems, that is, the number of negative samples is much larger than that of positive samples. Particularly, the data imbalance ph...

    Authors: Yongqing Zhang, Shaojie Qiao, Rongzhao Lu, Nan Han, Dingxiang Liu and Jiliu Zhou
    Citation: BMC Bioinformatics 2019 20(Suppl 25):695
  14. Along with the development of precision medicine, individual heterogeneity is attracting more and more attentions in clinical research and application. Although the biomolecular reaction seems to be some vario...

    Authors: Shaoyan Sun, Xiangtian Yu, Fengnan Sun, Ying Tang, Juan Zhao and Tao Zeng
    Citation: BMC Bioinformatics 2019 20(Suppl 25):697
  15. The recognition of protein interaction sites is of great significance in many biological processes, signaling pathways and drug designs. However, most sites on protein sequences cannot be defined as interface ...

    Authors: Ye Wang, Changqing Mei, Yuming Zhou, Yan Wang, Chunhou Zheng, Xiao Zhen, Yan Xiong, Peng Chen, Jun Zhang and Bing Wang
    Citation: BMC Bioinformatics 2019 20(Suppl 25):699
  16. Membrane proteins play an important role in the life activities of organisms. Knowing membrane protein types provides clues for understanding the structure and function of proteins. Though various computationa...

    Authors: Lei Guo, Shunfang Wang, Mingyuan Li and Zicheng Cao
    Citation: BMC Bioinformatics 2019 20(Suppl 25):700

Annual Journal Metrics

  • 2022 Citation Impact
    3.0 - 2-year Impact Factor
    4.3 - 5-year Impact Factor
    0.938 - SNIP (Source Normalized Impact per Paper)
    1.100 - SJR (SCImago Journal Rank)

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    19 days submission to first editorial decision for all manuscripts (Median)
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