Volume 13 Supplement 17

Eleventh International Conference on Bioinformatics (InCoB2012): Bioinformatics


Edited by Shoba Ranganathan, Christian Schönbach, Sissades Tongsima, Jonathan Chan and Tin Wee Tan

The articles in this supplement were supported by funding agencies as detailed in the Acknowledgement section of each article

Asia Pacific Bioinformatics Network (APBioNet) Eleventh International Conference on Bioinformatics (InCoB2012). Go to conference site.

Bangkok, Thailand

3-5 October 2012

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  1. Introduction

    InCoB2012 Conference: from biological data to knowledge to technological breakthroughs

    Ten years ago when Asia-Pacific Bioinformatics Network held the first International Conference on Bioinformatics (InCoB) in Bangkok its theme was North-South Networking. At that time InCoB aimed to provide bio...

    Christian Schönbach, Sissades Tongsima, Jonathan Chan, Vladimir Brusic, Tin Wee Tan and Shoba Ranganathan

    BMC Bioinformatics 2012 13(Suppl 17):S1

    Published on: 13 December 2012

  2. Proceedings

    Prediction and analysis of protein solubility using a novel scoring card method with dipeptide composition

    Existing methods for predicting protein solubility on overexpression in Escherichia coli advance performance by using ensemble classifiers such as two-stage support vector machine (SVM) based classifiers and a nu...

    Hui-Ling Huang, Phasit Charoenkwan, Te-Fen Kao, Hua-Chin Lee, Fang-Lin Chang, Wen-Lin Huang, Shinn-Jang Ho, Li-Sun Shu, Wen-Liang Chen and Shinn-Ying Ho

    BMC Bioinformatics 2012 13(Suppl 17):S3

    Published on: 13 December 2012

  3. Proceedings

    Discovery of a new class of inhibitors for the protein arginine deiminase type 4 (PAD4) by structure-based virtual screening

    Rheumatoid arthritis (RA) is an autoimmune disease with unknown etiology. Anticitrullinated protein autoantibody has been documented as a highly specific autoantibody associated with RA. Protein arginine deimi...

    Chian Ying Teo, Steven Shave, Adam Leow Thean Chor, Abu Bakar Salleh, Mohd Basyaruddin Bin Abdul Rahman, Malcolm D Walkinshaw and Bimo A Tejo

    BMC Bioinformatics 2012 13(Suppl 17):S4

    Published on: 13 December 2012

  4. Proceedings

    Multiple virtual screening approaches for finding new Hepatitis c virus RNA-dependent RNA polymerase inhibitors: Structure-based screens and molecular dynamics for the pursue of new poly pharmacological inhibitors

    The RNA polymerase NS5B of Hepatitis C virus (HCV) is a well-characterised drug target with an active site and four allosteric binding sites. This work presents a workflow for virtual screening and its applica...

    Mahmoud ElHefnawi, Mohammad ElGamacy and Mohamed Fares

    BMC Bioinformatics 2012 13(Suppl 17):S5

    Published on: 13 December 2012

  5. Proceedings

    Large-scale reverse docking profiles and their applications

    Reverse docking approaches have been explored in previous studies on drug discovery to overcome some problems in traditional virtual screening. However, current reverse docking approaches are problematic in th...

    Minho Lee and Dongsup Kim

    BMC Bioinformatics 2012 13(Suppl 17):S6

    Published on: 13 December 2012

  6. Proceedings

    Sanjeevini: a freely accessible web-server for target directed lead molecule discovery

    Computational methods utilizing the structural and functional information help to understand specific molecular recognition events between the target biomolecule and candidate hits and make it possible to desi...

    B Jayaram, Tanya Singh, Goutam Mukherjee, Abhinav Mathur, Shashank Shekhar and Vandana Shekhar

    BMC Bioinformatics 2012 13(Suppl 17):S7

    Published on: 13 December 2012

  7. Proceedings

    ChemEx: information extraction system for chemical data curation

    Manual chemical data curation from publications is error-prone, time consuming, and hard to maintain up-to-date data sets. Automatic information extraction can be used as a tool to reduce these problems. Since...

    Atima Tharatipyakul, Somrak Numnark, Duangdao Wichadakul and Supawadee Ingsriswang

    BMC Bioinformatics 2012 13(Suppl 17):S9

    Published on: 13 December 2012

  8. Proceedings

    Mapping small molecule binding data to structural domains

    Large-scale bioactivity/SAR Open Data has recently become available, and this has allowed new analyses and approaches to be developed to help address the productivity and translational gaps of current drug dis...

    Felix A Kruger, Raghd Rostom and John P Overington

    BMC Bioinformatics 2012 13(Suppl 17):S11

    Published on: 13 December 2012

  9. Proceedings

    Prediction of nuclear proteins using nuclear translocation signals proposed by probabilistic latent semantic indexing

    Identification of subcellular localization in proteins is crucial to elucidate cellular processes and molecular functions in a cell. However, given a tremendous amount of sequence data generated in the post-ge...

    Emily Chia-Yu Su, Jia-Ming Chang, Cheng-Wei Cheng, Ting-Yi Sung and Wen-Lian Hsu

    BMC Bioinformatics 2012 13(Suppl 17):S13

    Published on: 13 December 2012

  10. Proceedings

    Improved statistical model checking methods for pathway analysis

    Statistical model checking techniques have been shown to be effective for approximate model checking on large stochastic systems, where explicit representation of the state space is impractical. Importantly, t...

    Chuan Hock Koh, Sucheendra K Palaniappan, PS Thiagarajan and Limsoon Wong

    BMC Bioinformatics 2012 13(Suppl 17):S15

    Published on: 13 December 2012

  11. Proceedings

    CMPF: Class-switching minimized pathfinding in metabolic networks

    The metabolic network is an aggregation of enzyme catalyzed reactions that converts one compound to another. Paths in a metabolic network are a sequence of enzymes that describe how a chemical compound of inte...

    Kevin Lim and Limsoon Wong

    BMC Bioinformatics 2012 13(Suppl 17):S17

    Published on: 13 December 2012

  12. Proceedings

    An automatic device for detection and classification of malaria parasite species in thick blood film

    Current malaria diagnosis relies primarily on microscopic examination of Giemsa-stained thick and thin blood films. This method requires vigorously trained technicians to efficiently detect and classify the ma...

    Saowaluck Kaewkamnerd, Chairat Uthaipibull, Apichart Intarapanich, Montri Pannarut, Sastra Chaotheing and Sissades Tongsima

    BMC Bioinformatics 2012 13(Suppl 17):S18

    Published on: 13 December 2012

  13. Proceedings

    B-cell epitope prediction through a graph model

    Prediction of B-cell epitopes from antigens is useful to understand the immune basis of antibody-antigen recognition, and is helpful in vaccine design and drug development. Tremendous efforts have been devoted...

    Liang Zhao, Limsoon Wong, Lanyuan Lu, Steven CH Hoi and Jinyan Li

    BMC Bioinformatics 2012 13(Suppl 17):S20

    Published on: 13 December 2012

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