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Volume 20 Supplement 7

Selected papers from the 12th International Conference on Computational Systems Biology (ISB 2018)


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Guiyang, China18-21 August 2018

Conference website

Edited by Luonan Chen and Yong Wang.

  1. Content type: Research

    A key problem in systems biology is the determination of the regulatory mechanism corresponding to a phenotype. An empirical approach in this regard is to compare the expression profiles of cells under two con...

    Authors: Yance Feng, Sheng Zhang, Liang Li and Lei M. Li

    Citation: BMC Bioinformatics 2019 20(Suppl 7):201

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  2. Content type: Research

    Lipid metabolism reprogramming is a hallmark for tumor which contributes to tumorigenesis and progression, but the commonality and difference of lipid metabolism among pan-cancer is not fully investigated. Inc...

    Authors: Yang Hao, Daixi Li, Yong Xu, Jian Ouyang, Yongkun Wang, Yuqi Zhang, Baoguo Li, Lu Xie and Guangrong Qin

    Citation: BMC Bioinformatics 2019 20(Suppl 7):195

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  3. Content type: Research

    Transcription factors (TFs) play important roles in the regulation of gene expression. They can activate or block transcription of downstream genes in a manner of binding to specific genomic sequences. Therefo...

    Authors: Jialu Hu, Jingru Wang, Jianan Lin, Tianwei Liu, Yuanke Zhong, Jie Liu, Yan Zheng, Yiqun Gao, Junhao He and Xuequn Shang

    Citation: BMC Bioinformatics 2019 20(Suppl 7):200

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  4. Content type: Research

    The Iridoviridae family is categorized into five genera and clustered into two subfamilies: Alphairidovirinae includes Lymphocystivirus, Ranavirus (GIV), and Megalocystivirus (TGIV), which infect vertebrate hosts...

    Authors: Tao-Chuan Shih, Li-Ping Ho, Jen-Leih Wu, Hsin-Yiu Chou and Tun-Wen Pai

    Citation: BMC Bioinformatics 2019 20(Suppl 7):192

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  5. Content type: Research

    Experimental studies have demonstrated that both the extracellular vasculature or microenvironment and intracellular molecular network (e.g., epidermal growth factor receptor (EGFR) signaling pathway) are impo...

    Authors: Weishan Liang, Yongjiang Zheng, Ji Zhang and Xiaoqiang Sun

    Citation: BMC Bioinformatics 2019 20(Suppl 7):203

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  6. Content type: Research

    Most researches of chronic myeloid leukemia (CML) are currently focused on the treatment methods, while there are relatively few researches on the progress of patients’ condition after drug treatment. Traditio...

    Authors: Junhua Xu, Min Wu, Shanshan Zhu, Jinzhi Lei and Jie Gao

    Citation: BMC Bioinformatics 2019 20(Suppl 7):202

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  7. Content type: Research

    Haemorrhagic stroke accounts for approximately 31.52% of all stroke cases, and the most common origin is hypertension. However, little is known about the method to identify high-risk populations of hypertensiv...

    Authors: Le Zhang, Jin Li, Kaikai Yin, Zhouyang Jiang, Tingting Li, Rong Hu, Zheng Yu, Hua Feng and Yujie Chen

    Citation: BMC Bioinformatics 2019 20(Suppl 7):193

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  8. Content type: Research

    Drug adverse events (AEs), or called adverse drug events (ADEs), are ranked one of the leading causes of mortality. The Ontology of Adverse Events (OAE) has been widely used for adverse event AE representation...

    Authors: Hong Yu, Solomiya Nysak, Noemi Garg, Edison Ong, Xianwei Ye, Xiangyan Zhang and Yongqun He

    Citation: BMC Bioinformatics 2019 20(Suppl 7):199

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2018 Journal Metrics

  • Citation Impact
    2.511 - 2-year Impact Factor
    2.970 - 5-year Impact Factor
    0.855 - Source Normalized Impact per Paper (SNIP)
    1.374 - SCImago Journal Rank (SJR)


    Social Media Impact
    4446 mentions