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Volume 14 Supplement 14

Proceedings of the Tenth Annual MCBIOS Conference

Proceedings

Edited by Jonathan D Wren (Senior Editor), Mikhail G Dozmorov, Dennis Burian, Rakesh Kaundal, Andy Perkins, Ed Perkins, Doris M Kupfer and Gordon K Springer

Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. Articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Tenth Annual MCBIOS Conference. Discovery in a sea of data. Go to conference site.

Columbia, MO, USA5-6 April 2013

  1. Content type: Proceedings

    Even though only 1.5% of the human genome is translated into proteins, recent reports indicate that most of it is transcribed into non-coding RNAs (ncRNAs), which are becoming the subject of increased scientif...

    Authors: Mikhail G Dozmorov, Cory B Giles, Kristi A Koelsch and Jonathan D Wren

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S2

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  2. Content type: Proceedings

    Pathway alterations reflected as changes in gene expression regulation and gene interaction can result from cellular exposure to toxicants. Such information is often used to elucidate toxicological modes of ac...

    Authors: Yi Yang, Andrew Maxwell, Xiaowei Zhang, Nan Wang, Edward J Perkins, Chaoyang Zhang and Ping Gong

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S3

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  3. Content type: Proceedings

    Transcriptome analysis by microarrays has produced important advances in biomedicine. For instance in multiple myeloma (MM), microarray approaches led to the development of an effective disease subtyping via c...

    Authors: Shweta S Chavan, Michael A Bauer, Erich A Peterson, Christoph J Heuck and Donald J Johann Jr

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S4

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  4. Content type: Proceedings

    An important mechanism of endocrine activity is chemicals entering target cells via transport proteins and then interacting with hormone receptors such as the estrogen receptor (ER). α-Fetoprotein (AFP) is a m...

    Authors: Jie Shen, Wenqian Zhang, Hong Fang, Roger Perkins, Weida Tong and Huixiao Hong

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S6

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  5. Content type: Proceedings

    Plastids are an important component of plant cells, being the site of manufacture and storage of chemical compounds used by the cell, and contain pigments such as those used in photosynthesis, starch synthesis...

    Authors: Rakesh Kaundal, Sitanshu S Sahu, Ruchi Verma and Tyler Weirick

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S7

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  6. Content type: Proceedings

    The advances in high throughput omics technologies have made it possible to characterize molecular interactions within and across various species. Alignments and comparison of molecular networks across species...

    Authors: Jialiang Yang, Jun Li, Stefan Grünewald and Xiu-Feng Wan

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S8

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  7. Content type: Proceedings

    Dicer, an RNase III enzyme, plays a vital role in the processing of pre-miRNAs for generating the miRNAs. The structural and sequence features on pre-miRNA which can facilitate position and efficiency of cleav...

    Authors: Firoz Ahmed, Rakesh Kaundal and Gajendra PS Raghava

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S9

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  8. Content type: Proceedings

    Advances in technology have led to the generation of massive amounts of complex and multifarious biological data in areas ranging from genomics to structural biology. The volume and complexity of such data lea...

    Authors: Rahul Singh, Hui Yang, Ben Dalziel, Daniel Asarnow, William Murad, David Foote, Matthew Gormley, Jonathan Stillman and Susan Fisher

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S10

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  9. Content type: Proceedings

    High Content Screening (HCS) has become an important tool for toxicity assessment, partly due to its advantage of handling multiple measurements simultaneously. This approach has provided insight and contribut...

    Authors: Halil Bisgin, Minjun Chen, Yuping Wang, Reagan Kelly, Hong Fang, Xiaowei Xu and Weida Tong

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S11

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  10. Content type: Proceedings

    Reversible posttranslational protein modifications such as phosphorylation of Ser/Thr/Tyr and Met oxidation are critical for both metabolic regulation and cellular signalling. Although these modifications are ...

    Authors: R Shyama Prasad Rao, Dong Xu, Jay J Thelen and Ján A Miernyk

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S14

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  11. Content type: Proceedings

    Pulsed field gel electrophoresis (PFGE) is currently the most widely and routinely used method by the Centers for Disease Control and Prevention (CDC) and state health labs in the United States for Salmonella sur...

    Authors: Wen Zou, Hailin Tang, Weizhong Zhao, Joe Meehan, Steven L Foley, Wei-Jiun Lin, Hung-Chia Chen, Hong Fang, Rajesh Nayak and James J Chen

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S15

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  12. Content type: Proceedings

    In drug discovery and development, it is crucial to determine which conformers (instances) of a given molecule are responsible for its observed biological activity and at the same time to recognize the most re...

    Authors: Zhendong Zhao, Gang Fu, Sheng Liu, Khaled M Elokely, Robert J Doerksen, Yixin Chen and Dawn E Wilkins

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S16

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  13. Content type: Proceedings

    Experimentally validated co-expression correlations between miRNAs and genes are a valuable resource to corroborate observations about miRNA/mRNA changes after experimental perturbations, as well as compare mi...

    Authors: Cory B Giles, Reshmi Girija-Devi, Mikhail G Dozmorov and Jonathan D Wren

    Citation: BMC Bioinformatics 2013 14(Suppl 14):S17

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