Volume 14 Supplement 14

Proceedings of the Tenth Annual MCBIOS Conference


Edited by Jonathan D Wren (Senior Editor), Mikhail G Dozmorov, Dennis Burian, Rakesh Kaundal, Andy Perkins, Ed Perkins, Doris M Kupfer and Gordon K Springer

Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. Articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Tenth Annual MCBIOS Conference. Discovery in a sea of data. Go to conference site.

Columbia, MO, USA

5-6 April 2013

  1. Proceedings

    Systematic classification of non-coding RNAs by epigenomic similarity

    Even though only 1.5% of the human genome is translated into proteins, recent reports indicate that most of it is transcribed into non-coding RNAs (ncRNAs), which are becoming the subject of increased scientif...

    Mikhail G Dozmorov, Cory B Giles, Kristi A Koelsch and Jonathan D Wren

    BMC Bioinformatics 2013 14(Suppl 14):S2

    Published on: 9 October 2013

  2. Proceedings

    Differential reconstructed gene interaction networks for deriving toxicity threshold in chemical risk assessment

    Pathway alterations reflected as changes in gene expression regulation and gene interaction can result from cellular exposure to toxicants. Such information is often used to elucidate toxicological modes of ac...

    Yi Yang, Andrew Maxwell, Xiaowei Zhang, Nan Wang, Edward J Perkins, Chaoyang Zhang and Ping Gong

    BMC Bioinformatics 2013 14(Suppl 14):S3

    Published on: 9 October 2013

  3. Proceedings

    Towards the integration, annotation and association of historical microarray experiments with RNA-seq

    Transcriptome analysis by microarrays has produced important advances in biomedicine. For instance in multiple myeloma (MM), microarray approaches led to the development of an effective disease subtyping via c...

    Shweta S Chavan, Michael A Bauer, Erich A Peterson, Christoph J Heuck and Donald J Johann Jr

    BMC Bioinformatics 2013 14(Suppl 14):S4

    Published on: 9 October 2013

  4. Proceedings

    Homology modeling, molecular docking, and molecular dynamics simulations elucidated α-fetoprotein binding modes

    An important mechanism of endocrine activity is chemicals entering target cells via transport proteins and then interacting with hormone receptors such as the estrogen receptor (ER). α-Fetoprotein (AFP) is a m...

    Jie Shen, Wenqian Zhang, Hong Fang, Roger Perkins, Weida Tong and Huixiao Hong

    BMC Bioinformatics 2013 14(Suppl 14):S6

    Published on: 9 October 2013

  5. Proceedings

    BinAligner: a heuristic method to align biological networks

    The advances in high throughput omics technologies have made it possible to characterize molecular interactions within and across various species. Alignments and comparison of molecular networks across species...

    Jialiang Yang, Jun Li, Stefan Grünewald and Xiu-Feng Wan

    BMC Bioinformatics 2013 14(Suppl 14):S8

    Published on: 9 October 2013

  6. Proceedings

    Towards human-computer synergetic analysis of large-scale biological data

    Advances in technology have led to the generation of massive amounts of complex and multifarious biological data in areas ranging from genomics to structural biology. The volume and complexity of such data lea...

    Rahul Singh, Hui Yang, Ben Dalziel, Daniel Asarnow, William Murad, David Foote, Matthew Gormley, Jonathan Stillman and Susan Fisher

    BMC Bioinformatics 2013 14(Suppl 14):S10

    Published on: 9 October 2013

  7. Proceedings

    Data mining tools for Salmonella characterization: application to gel-based fingerprinting analysis

    Pulsed field gel electrophoresis (PFGE) is currently the most widely and routinely used method by the Centers for Disease Control and Prevention (CDC) and state health labs in the United States for Salmonella sur...

    Wen Zou, Hailin Tang, Weizhong Zhao, Joe Meehan, Steven L Foley, Wei-Jiun Lin, Hung-Chia Chen, Hong Fang, Rajesh Nayak and James J Chen

    BMC Bioinformatics 2013 14(Suppl 14):S15

    Published on: 9 October 2013

  8. Proceedings

    Drug activity prediction using multiple-instance learning via joint instance and feature selection

    In drug discovery and development, it is crucial to determine which conformers (instances) of a given molecule are responsible for its observed biological activity and at the same time to recognize the most re...

    Zhendong Zhao, Gang Fu, Sheng Liu, Khaled M Elokely, Robert J Doerksen, Yixin Chen and Dawn E Wilkins

    BMC Bioinformatics 2013 14(Suppl 14):S16

    Published on: 9 October 2013