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Volume 7 Supplement 2

Third Annual MCBIOS Conference. Bioinformatics: A Calculated Discovery

Proceedings

Edited by Jonathan D Wren (Senior Editor), Stephen Winters-Hilt, Yuriy Gusev, Andrey Ptitsyn

Third Annual MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference. Bioinformatics: A Calculated Discovery.

Baton Rouge, LA, USA2-4 March, 2006

  1. Naturally occurring antimicrobial peptides are currently being explored as potential candidate peptide drugs. Since antimicrobial peptides are part of the innate immune system of every living organism, it is p...

    Authors: Vijayaraj Nagarajan, Navodit Kaushik, Beddhu Murali, Chaoyang Zhang, Sanyogita Lakhera, Mohamed O Elasri and Youping Deng
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S2
  2. We describe Support Vector Machine (SVM) applications to classification and clustering of channel current data. SVMs are variational-calculus based methods that are constrained to have structural risk minimiza...

    Authors: Stephen Winters-Hilt, Anil Yelundur, Charlie McChesney and Matthew Landry
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S4
  3. Catalytic RNA molecules are called ribozymes. The aptamers are DNA or RNA molecules that have been selected from vast populations of random sequences, through a combinatorial approach known as SELEX. The selec...

    Authors: Venkata Thodima, Mehdi Pirooznia and Youping Deng
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S6
  4. Evolutionary genomics requires management and filtering of large numbers of diverse genomic sequences for accurate analysis and inference on evolutionary processes of genomic and functional change. We developed E

    Authors: Laila A Nahum, Matthew T Reynolds, Zhengyuan O Wang, Jeremiah J Faith, Rahul Jonna, Zhi J Jiang, Thomas J Meyer and David D Pollock
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S7
  5. Independent Component Analysis (ICA) proves to be useful in the analysis of neural activity, as it allows for identification of distinct sources of activity. Applied to measurements registered in a controlled ...

    Authors: Tomasz G Smolinski, Roger Buchanan, Grzegorz M Boratyn, Mariofanna Milanova and Astrid A Prinz
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S8
  6. The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the large colonies grow at a normal rate while cell...

    Authors: Tao Han, Jianyong Wang, Weida Tong, Martha M Moore, James C Fuscoe and Tao Chen
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S9
  7. Periodic processes, such as the circadian rhythm, are important factors modulating and coordinating transcription of genes governing key metabolic pathways. Theoretically, even small fluctuations in the orches...

    Authors: Andrey A Ptitsyn, Sanjin Zvonic and Jeffrey M Gimble
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S10
  8. In studies that use DNA arrays to assess changes in gene expression, our goal is to evaluate the statistical significance of treatments on sets of genes. Genes can be grouped by a molecular function, a biologi...

    Authors: Robert Delongchamp, Taewon Lee and Cruz Velasco
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S11
  9. Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cells. Transcription factors constitute a class of the r...

    Authors: Alexdander Kel, Nico Voss, Ruy Jauregui, Olga Kel-Margoulis and Edgar Wingender
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S13
  10. Markov statistical methods may make it possible to develop an unsupervised learning process that can automatically identify genomic structure in prokaryotes in a comprehensive way. This approach is based on mu...

    Authors: Stephen Winters-Hilt
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S14
  11. We present a novel strategy for classification of DNA molecules using measurements from an alpha-Hemolysin channel detector. The proposed approach provides excellent classification performance for five differe...

    Authors: Raja Tanveer Iqbal, Matthew Landry and Stephen Winters-Hilt
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S15
  12. Comfrey is consumed by humans as a vegetable and a tea, and has been used as an herbal medicine for more than 2000 years. Comfrey, however, is hepatotoxic in livestock and humans and carcinogenic in experiment...

    Authors: Nan Mei, Lei Guo, Lu Zhang, Leming Shi, Yongming Andrew Sun, Chris Fung, Carrie L Moland, Stacey L Dial, James C Fuscoe and Tao Chen
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S16
  13. DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in response to drugs and toxins. This is leading ...

    Authors: Tao Han, Cathy D Melvin, Leming Shi, William S Branham, Carrie L Moland, P Scott Pine, Karol L Thompson and James C Fuscoe
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S17
  14. Fibrates are a unique hypolipidemic drugs that lower plasma triglyceride and cholesterol levels through their action as peroxisome proliferator-activated receptor alpha (PPARα) agonists. The activation of PPAR...

    Authors: Lei Guo, Hong Fang, Jim Collins, Xiao-hui Fan, Stacey Dial, Alex Wong, Kshama Mehta, Ernice Blann, Leming Shi, Weida Tong and Yvonne P Dragan
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S18
  15. Aristolochic acid (AA) is the active component of herbal drugs derived from Aristolochia species that have been used for medicinal purposes since antiquity. AA, however, induced nephropathy and urothelial cancer ...

    Authors: Tao Chen, Lei Guo, Lu Zhang, Leming Shi, Hong Fang, Yongming Sun, James C Fuscoe and Nan Mei
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S20
  16. Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This information is derived from observation of changes in...

    Authors: Stephen Winters-Hilt, Matthew Landry, Mark Akeson, Maria Tanase, Iftekhar Amin, Amy Coombs, Eric Morales, John Millet, Carl Baribault and Srikanth Sendamangalam
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S22
  17. Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular components, facilitating interpretation of data fr...

    Authors: Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins and Weida Tong
    Citation: BMC Bioinformatics 2006 7(Suppl 2):S23

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 2.9
    5-year Journal Impact Factor: 3.6
    Source Normalized Impact per Paper (SNIP): 0.821
    SCImago Journal Rank (SJR): 1.005

    Speed 2023
    Submission to first editorial decision (median days): 12
    Submission to acceptance (median days): 146

    Usage 2023
    Downloads: 5,987,678
    Altmetric mentions: 4,858

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