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BMC Bioinformatics

Volume 7 Supplement 2

Third Annual MCBIOS Conference. Bioinformatics: A Calculated Discovery

Proceedings

Edited by Jonathan D Wren (Senior Editor), Stephen Winters-Hilt, Yuriy Gusev, Andrey Ptitsyn

Third Annual MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference. Bioinformatics: A Calculated Discovery.

Baton Rouge, LA, USA2-4 March, 2006

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  1. Content type: Proceedings

    Naturally occurring antimicrobial peptides are currently being explored as potential candidate peptide drugs. Since antimicrobial peptides are part of the innate immune system of every living organism, it is p...

    Authors: Vijayaraj Nagarajan, Navodit Kaushik, Beddhu Murali, Chaoyang Zhang, Sanyogita Lakhera, Mohamed O Elasri and Youping Deng

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S2

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  2. Content type: Proceedings

    We describe Support Vector Machine (SVM) applications to classification and clustering of channel current data. SVMs are variational-calculus based methods that are constrained to have structural risk minimiza...

    Authors: Stephen Winters-Hilt, Anil Yelundur, Charlie McChesney and Matthew Landry

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S4

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  3. Content type: Proceedings

    Catalytic RNA molecules are called ribozymes. The aptamers are DNA or RNA molecules that have been selected from vast populations of random sequences, through a combinatorial approach known as SELEX. The selec...

    Authors: Venkata Thodima, Mehdi Pirooznia and Youping Deng

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S6

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  4. Content type: Proceedings

    Evolutionary genomics requires management and filtering of large numbers of diverse genomic sequences for accurate analysis and inference on evolutionary processes of genomic and functional change. We developed E

    Authors: Laila A Nahum, Matthew T Reynolds, Zhengyuan O Wang, Jeremiah J Faith, Rahul Jonna, Zhi J Jiang, Thomas J Meyer and David D Pollock

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S7

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  5. Content type: Proceedings

    Independent Component Analysis (ICA) proves to be useful in the analysis of neural activity, as it allows for identification of distinct sources of activity. Applied to measurements registered in a controlled ...

    Authors: Tomasz G Smolinski, Roger Buchanan, Grzegorz M Boratyn, Mariofanna Milanova and Astrid A Prinz

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S8

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  6. Content type: Proceedings

    The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the large colonies grow at a normal rate while cell...

    Authors: Tao Han, Jianyong Wang, Weida Tong, Martha M Moore, James C Fuscoe and Tao Chen

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S9

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  7. Content type: Proceedings

    Periodic processes, such as the circadian rhythm, are important factors modulating and coordinating transcription of genes governing key metabolic pathways. Theoretically, even small fluctuations in the orches...

    Authors: Andrey A Ptitsyn, Sanjin Zvonic and Jeffrey M Gimble

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S10

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  8. Content type: Proceedings

    In studies that use DNA arrays to assess changes in gene expression, our goal is to evaluate the statistical significance of treatments on sets of genes. Genes can be grouped by a molecular function, a biologi...

    Authors: Robert Delongchamp, Taewon Lee and Cruz Velasco

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S11

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  9. Content type: Proceedings

    Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cells. Transcription factors constitute a class of the r...

    Authors: Alexdander Kel, Nico Voss, Ruy Jauregui, Olga Kel-Margoulis and Edgar Wingender

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S13

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  10. Content type: Proceedings

    Markov statistical methods may make it possible to develop an unsupervised learning process that can automatically identify genomic structure in prokaryotes in a comprehensive way. This approach is based on mu...

    Authors: Stephen Winters-Hilt

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S14

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  11. Content type: Proceedings

    We present a novel strategy for classification of DNA molecules using measurements from an alpha-Hemolysin channel detector. The proposed approach provides excellent classification performance for five differe...

    Authors: Raja Tanveer Iqbal, Matthew Landry and Stephen Winters-Hilt

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S15

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  12. Content type: Proceedings

    Comfrey is consumed by humans as a vegetable and a tea, and has been used as an herbal medicine for more than 2000 years. Comfrey, however, is hepatotoxic in livestock and humans and carcinogenic in experiment...

    Authors: Nan Mei, Lei Guo, Lu Zhang, Leming Shi, Yongming Andrew Sun, Chris Fung, Carrie L Moland, Stacey L Dial, James C Fuscoe and Tao Chen

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S16

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  13. Content type: Proceedings

    DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in response to drugs and toxins. This is leading ...

    Authors: Tao Han, Cathy D Melvin, Leming Shi, William S Branham, Carrie L Moland, P Scott Pine, Karol L Thompson and James C Fuscoe

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S17

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  14. Content type: Proceedings

    Fibrates are a unique hypolipidemic drugs that lower plasma triglyceride and cholesterol levels through their action as peroxisome proliferator-activated receptor alpha (PPAR╬▒) agonists. The activation of PPAR...

    Authors: Lei Guo, Hong Fang, Jim Collins, Xiao-hui Fan, Stacey Dial, Alex Wong, Kshama Mehta, Ernice Blann, Leming Shi, Weida Tong and Yvonne P Dragan

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S18

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  15. Content type: Proceedings

    Aristolochic acid (AA) is the active component of herbal drugs derived from Aristolochia species that have been used for medicinal purposes since antiquity. AA, however, induced nephropathy and urothelial cancer ...

    Authors: Tao Chen, Lei Guo, Lu Zhang, Leming Shi, Hong Fang, Yongming Sun, James C Fuscoe and Nan Mei

    Citation: BMC Bioinformatics 2006 7(Suppl 2):S20

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