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BMC Bioinformatics

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  1. Content type: Research

    Essential proteins are indispensable to the survival and development process of living organisms. To understand the functional mechanisms of essential proteins, which can be applied to the analysis of disease ...

    Authors: Yetian Fan, Xiwei Tang, Xiaohua Hu, Wei Wu and Qing Ping

    Citation: BMC Bioinformatics 2017 18(Suppl 13):470

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 13

  2. Content type: Methodology Article

    Transcription factors (TFs) form a complex regulatory network within the cell that is crucial to cell functioning and human health. While methods to establish where a TF binds to DNA are well established, thes...

    Authors: Maxwell Spadafore, Kayvan Najarian and Alan P. Boyle

    Citation: BMC Bioinformatics 2017 18:530

    Published on:

  3. Content type: Software

    ImageJ is an image analysis program extensively used in the biological sciences and beyond. Due to its ease of use, recordable macro language, and extensible plug-in architecture, ImageJ enjoys contributions f...

    Authors: Curtis T. Rueden, Johannes Schindelin, Mark C. Hiner, Barry E. DeZonia, Alison E. Walter, Ellen T. Arena and Kevin W. Eliceiri

    Citation: BMC Bioinformatics 2017 18:529

    Published on:

  4. Content type: Methodology Article

    High-throughput sequencing offers higher throughput and lower cost for sequencing a genome. However, sequencing errors, including mismatches and indels, may be produced during sequencing. Because, errors may r...

    Authors: Yao-Ting Huang and Yu-Wen Huang

    Citation: BMC Bioinformatics 2017 18:524

    Published on:

  5. Content type: Research Article

    Cell-scaffold contact measurements are derived from pairs of co-registered volumetric fluorescent confocal laser scanning microscopy (CLSM) images (z-stacks) of stained cells and three types of scaffolds (i.e....

    Authors: Peter Bajcsy, Soweon Yoon, Stephen J. Florczyk, Nathan A. Hotaling, Mylene Simon, Piotr M. Szczypinski, Nicholas J. Schaub, Carl G. Simon Jr, Mary Brady and Ram D. Sriram

    Citation: BMC Bioinformatics 2017 18:526

    Published on:

  6. Content type: Software

    Chromatin immunoprecipitation followed by DNA sequencing (ChIP-seq) and associated methods are widely used to define the genome wide distribution of chromatin associated proteins, post-translational epigenetic...

    Authors: Mike Myschyshyn, Marco Farren-Dai, Tien-Jui Chuang and David Vocadlo

    Citation: BMC Bioinformatics 2017 18:521

    Published on:

  7. Content type: Software

    Bioinformatics tools designed to identify lentiviral or retroviral vector insertion sites in the genome of host cells are used to address the safety and long-term efficacy of hematopoietic stem cell gene thera...

    Authors: Giulio Spinozzi, Andrea Calabria, Stefano Brasca, Stefano Beretta, Ivan Merelli, Luciano Milanesi and Eugenio Montini

    Citation: BMC Bioinformatics 2017 18:520

    Published on:

  8. Content type: Methodology Article

    Accurate structural annotation depends on well-trained gene prediction programs. Training data for gene prediction programs are often chosen randomly from a subset of high-quality genes that ideally represent ...

    Authors: Megan J. Bowman, Jane A. Pulman, Tiffany L. Liu and Kevin L. Childs

    Citation: BMC Bioinformatics 2017 18:522

    Published on:

  9. Content type: Software

    Gene regulatory networks govern the function of key cellular processes, such as control of the cell cycle, response to stress, DNA repair mechanisms, and more. Boolean networks have been used successfully in m...

    Authors: Levi D. Mcclenny, Mahdi Imani and Ulisses M. Braga-Neto

    Citation: BMC Bioinformatics 2017 18:519

    Published on:

  10. Content type: Software

    With the plummeting cost of the next-generation sequencing technologies, high-density genetic linkage maps could be constructed in a forest hybrid F1 population. However, based on such genetic maps, quantitative ...

    Authors: Fenxiang Liu, Chunfa Tong, Shentong Tao, Jiyan Wu, Yuhua Chen, Dan Yao, Huogen Li and Jisen Shi

    Citation: BMC Bioinformatics 2017 18:515

    Published on:

  11. Content type: Research Article

    Mantle Cell Lymphoma (MCL) is a B cell aggressive neoplasia accounting for about the 6% of all lymphomas. The most common molecular marker of clonality in MCL, as in other B lymphoproliferative disorders, is t...

    Authors: Marco Beccuti, Elisa Genuardi, Greta Romano, Luigia Monitillo, Daniela Barbero, Mario Boccadoro, Marco Ladetto, Raffaele Calogero, Simone Ferrero and Francesca Cordero

    Citation: BMC Bioinformatics 2017 18:516

    Published on:

  12. Content type: Methodology Article

    Gene set enrichment analysis and overrepresentation analyses are commonly used methods to determine the biological processes affected by a differential expression experiment. This approach requires biologicall...

    Authors: Jie Tan, Matthew Huyck, Dongbo Hu, René A. Zelaya, Deborah A. Hogan and Casey S. Greene

    Citation: BMC Bioinformatics 2017 18:512

    Published on:

  13. Content type: Research Article

    Nowadays, many public repositories containing large microarray gene expression datasets are available. However, the problem lies in the fact that microarray technology are less powerful and accurate than more ...

    Authors: Daniel Castillo, Juan Manuel Gálvez, Luis Javier Herrera, Belén San Román, Fernando Rojas and Ignacio Rojas

    Citation: BMC Bioinformatics 2017 18:506

    Published on:

  14. Content type: Methodology Article

    The sequence of nucleotides in an RNA determines the possible base pairs for an RNA fold and thus also determines the overall shape and function of an RNA. The Swellix program presented here combines a helix a...

    Authors: Nathan Sloat, Jui-Wen Liu and Susan J. Schroeder

    Citation: BMC Bioinformatics 2017 18:504

    Published on:

  15. Content type: Research Article

    Brain disorders are one of the top causes of human death. Generally, neurologists analyze brain medical images for diagnosis. In the image analysis field, corners are one of the most important features, which ...

    Authors: Linlin Gao, Haiwei Pan, Qing Li, Xiaoqin Xie, Zhiqiang Zhang, Jinming Han and Xiao Zhai

    Citation: BMC Bioinformatics 2017 18:505

    Published on:

  16. Content type: Software

    Whole-genome sequencing (WGS) projects provide short read nucleotide sequences from nuclear and possibly organelle DNA depending on the source of origin. Mitochondrial DNA is present in animals and fungi, whil...

    Authors: Kosai Al-Nakeeb, Thomas Nordahl Petersen and Thomas Sicheritz-Pontén

    Citation: BMC Bioinformatics 2017 18:510

    Published on:

  17. Content type: Software

    ANAT is a graphical, Cytoscape-based tool for the inference of protein networks that underlie a process of interest. The ANAT tool allows the user to perform network reconstruction under several scenarios in a...

    Authors: Yomtov Almozlino, Nir Atias, Dana Silverbush and Roded Sharan

    Citation: BMC Bioinformatics 2017 18:495

    Published on:

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2016 Journal Metrics

  • Citation Impact
    2.448 - 2-year Impact Factor
    3.450 - 5-year Impact Factor
    0.946 - Source Normalized Impact per Paper (SNIP)
    1.467 - SCImago Journal Rank (SJR)

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    1405 Usage Factor


    Social Media Impact
    816 mentions

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