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BMC Bioinformatics

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  1. Content type: Software

    Protein cavities play a key role in biomolecular recognition and function, particularly in protein-ligand interactions, as usual in drug discovery and design. Grid-based cavity detection methods aim at finding...

    Authors: Sérgio E. D. Dias, Ana Mafalda Martins, Quoc T. Nguyen and Abel J. P. Gomes

    Citation: BMC Bioinformatics 2017 18:493

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  2. Content type: Database

    Autism spectrum disorders (ASD) are hereditary, heterogeneous and biologically complex neurodevelopmental disorders. Individual studies on gene expression in ASD cannot provide clear consensus conclusions. The...

    Authors: Shuyun Zhang, Libin Deng, Qiyue Jia, Shaoting Huang, Junwang Gu, Fankun Zhou, Meng Gao, Xinyi Sun, Chang Feng and Guangqin Fan

    Citation: BMC Bioinformatics 2017 18:494

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  3. Content type: Methodology Article

    The advent of array-based genome-wide DNA methylation methods has enabled quantitative measurement of single CpG methylation status at relatively low cost and sample input. Whereas the use of Infinium Human Me...

    Authors: Maria Needhamsen, Ewoud Ewing, Harald Lund, David Gomez-Cabrero, Robert Adam Harris, Lara Kular and Maja Jagodic

    Citation: BMC Bioinformatics 2017 18:486

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  4. Content type: Correction

    After publication of this supplement [1], it was brought to our attention that the wrong year was used in the title of the supplement. The 16th Annual UT-KBRIN Bioinformatics Summit was held in 2017.

    Authors: Eric C. Rouchka, Julia L. Chariker, David Tieri and Juw W. Park

    Citation: BMC Bioinformatics 2017 18:490

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    The original article was published in BMC Bioinformatics 2017 18:377

  5. Content type: Research Article

    With the development of chromosomal conformation capturing techniques, particularly, the Hi-C technique, the study of the spatial conformation of a genome is becoming an important topic in bioinformatics and c...

    Authors: Oluwatosin Oluwadare and Jianlin Cheng

    Citation: BMC Bioinformatics 2017 18:480

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  6. Content type: Research Article

    MicroRNAs (miRNAs) have been shown to play an important role in pathological initiation, progression and maintenance. Because identification in the laboratory of disease-related miRNAs is not straightforward, ...

    Authors: Duc-Hau Le, Lieven Verbeke, Le Hoang Son, Dinh-Toi Chu and Van-Huy Pham

    Citation: BMC Bioinformatics 2017 18:479

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  7. Content type: Research Article

    Gene expression profiling has led to the definition of breast cancer molecular subtypes: Basal-like, HER2-enriched, LuminalA, LuminalB and Normal-like. Different subtypes exhibit diverse responses to treatment...

    Authors: Liying Yang, Yunyan Shen, Xiguo Yuan, Junying Zhang and Jianhua Wei

    Citation: BMC Bioinformatics 2017 18:481

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  8. Content type: Software

    The traditional method of visualizing gene annotation data in JBrowse is converting GFF3 files to JSON format, which is time-consuming. The latest version of JBrowse supports rendering sorted GFF3 files indexe...

    Authors: Tao Zhu, Chengzhen Liang, Zhigang Meng, Sandui Guo and Rui Zhang

    Citation: BMC Bioinformatics 2017 18:482

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  9. Content type: Methodology Article

    Single-particle analysis of electron cryo-microscopy (cryo-EM) is a key technology for elucidation of macromolecular structures. Recent technical advances in hardware and software developments significantly en...

    Authors: Jochen Ismer, Alexander S. Rose, Johanna K. S. Tiemann and Peter W. Hildebrand

    Citation: BMC Bioinformatics 2017 18:475

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  10. Content type: Software

    Large scale bacterial sequencing has made the determination of genetic relationships within large sequence collections of bacterial genomes derived from the same microbial species an increasingly common task. ...

    Authors: Oriol Mazariegos-Canellas, Trien Do, Tim Peto, David W. Eyre, Anthony Underwood, Derrick Crook and David H. Wyllie

    Citation: BMC Bioinformatics 2017 18:477

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  11. Content type: Methodology Article

    Artificially synthesized RNA molecules provide important ways for creating a variety of novel functional molecules. State-of-the-art RNA inverse folding algorithms can design simple and short RNA sequences of ...

    Authors: Xiufeng Yang, Kazuki Yoshizoe, Akito Taneda and Koji Tsuda

    Citation: BMC Bioinformatics 2017 18:468

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  12. Content type: Methodology Article

    De novo transcriptome assembly is an important technique for understanding gene expression in non-model organisms. Many de novo assemblers using the de Bruijn graph of a set of the RNA sequences rely on in-mem...

    Authors: Chang Sik Kim, Martyn D. Winn, Vipin Sachdeva and Kirk E. Jordan

    Citation: BMC Bioinformatics 2017 18:467

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  13. Content type: Research Article

    Biomedical named entity recognition(BNER) is a crucial initial step of information extraction in biomedical domain. The task is typically modeled as a sequence labeling problem. Various machine learning algori...

    Authors: Chen Lyu, Bo Chen, Yafeng Ren and Donghong Ji

    Citation: BMC Bioinformatics 2017 18:462

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  14. Content type: Database

    Using high-throughput sequencing to monitor translation in vivo, ribosome profiling can provide critical insights into the dynamics and regulation of protein synthesis in a cell. Since its introduction in 2009...

    Authors: Oana Carja, Tongji Xing, Edward W. J. Wallace, Joshua B. Plotkin and Premal Shah

    Citation: BMC Bioinformatics 2017 18:461

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  15. Content type: Methodology Article

    Somatic mutations accumulate in human cells throughout life. Some may have no adverse consequences, but some of them may lead to cancer. A cancer genome is typically unstable, and thus more mutations can accum...

    Authors: Yahya Bokhari and Tomasz Arodz

    Citation: BMC Bioinformatics 2017 18:458

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  16. Content type: Methodology Article

    Detection of important functional and/or structural elements and identification of their positions in a large eukaryotic genomic sequence are an active research area. Gene is an important functional and struct...

    Authors: Biswanath Chowdhury, Arnav Garai and Gautam Garai

    Citation: BMC Bioinformatics 2017 18:460

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2016 Journal Metrics

  • Citation Impact
    2.448 - 2-year Impact Factor
    3.450 - 5-year Impact Factor
    0.946 - Source Normalized Impact per Paper (SNIP)
    1.467 - SCImago Journal Rank (SJR)

    1405 Usage Factor

    Social Media Impact
    816 mentions